Results 61 to 70 of about 3,380,457 (302)

Risk of cardiovascular disease in a traditional African population with a high infectious load: a population-based study. [PDF]

PLoS ONE, 2012
BACKGROUND: To test the inflammatory origin of cardiovascular disease, as opposed to its origin in western lifestyle. Population-based assessment of the prevalences of cardiovascular risk factors and cardiovascular disease in an inflammation-prone ...
Jacob J E Koopman, David van Bodegom, J Wouter Jukema, Rudi G J Westendorp   +3 more
doaj   +1 more source

Genetic diversity, population structure, and traditional culture of Camellia reticulata [PDF]

Ecology and Evolution, 2017
AbstractCamellia reticulata is an arbor tree that has been cultivated in southwestern China by various sociolinguistic groups for esthetic purposes as well as to derive an edible seed oil. This study examined the influence of management, socio‐economic factors, and religion on the genetic diversity patterns of Camellia reticulata utilizing a ...
Tong Xin, Weijuan Huang, Jan De Riek, Shuang Zhang, Selena Ahmed, Johan Van Huylenbroeck, Chunlin Long   +6 more
openaire   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Transition in metabolic health phenotypes across general adiposity categories and association with the risk of depression: a prospective analysis

European Psychiatry
Background The association between obesity and depression may partly depend on the contextual metabolic health. The effect of change in metabolic health status over time on subsequent depression risk remains unclear.
Yunyi Zhu, Yuan Yin, Fei Huang, Yuanjun Liu, Yuge Xia, Mingying Zhang, Yunhe Wang, Lijuan Jin   +7 more
doaj   +1 more source

Population Genetic Structure of Traditional Populations in the Peruvian Central Andes and Implications for South American Population History [PDF]

Human Biology, 2014
Molecular-based characterizations of Andean peoples are traditionally conducted in the service of elucidating continent-level evolutionary processes in South America. Consequently, genetic variation among "western" Andean populations is often represented in relation to variation among "eastern" Amazon and Orinoco River Basin populations. This west-east
Graciela S, Cabana, Cecil M, Lewis, Raúl Y, Tito, R Alan, Covey, Angela M, Cáceres, Augusto F De La, Cruz, Diana, Durand, Genevieve, Housman, Brannon I, Hulsey, Gian Carlo, Iannacone, Paul W, López, Rolando, Martínez, Ángel, Medina, Olimpio Ortega, Dávila, Karla Paloma Osorio, Pinto, Susan I Polo, Santillán, Percy Rojas, Domínguez, Meagan, Rubel, Heather F, Smith, Silvia E, Smith, Verónica Rubín de Celis, Massa, Beatriz, Lizárraga, Anne C, Stone   +22 more
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Utility of traditional and non-traditional lipid indicators in the diagnosis of nonalcoholic fatty liver disease in a Japanese population

Lipids in Health and Disease, 2022
Background Traditional and non-traditional (TNNT) lipid indicators are known to be closely related to nonalcoholic fatty liver disease (NAFLD). This study’s objective was to compare the degree of associations and diagnostic values of TNNT lipid ...
Song Lu, Maobin Kuang, Jinjing Yue, Chong Hu, Guotai Sheng, Yang Zou   +5 more
doaj   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Spatial distribution analysis and driving factors of traditional villages in Henan province: a comprehensive approach via geospatial techniques and statistical models

Heritage Science, 2023
Traditional villages are repositories for preserving human artifacts and cultural heritage. An investigation of the spatial distribution characteristics and factors influencing traditional villages in provincial administrative regions can provide new ...
Wenxiang Liu, Ying Xue, Cun Shang
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source