Results 91 to 100 of about 41,264 (308)
Sovremennye Issledovaniâ Socialʹnyh Problem, 2013 The modern Russian society is under influence of globalization and traditionalism threats that have serious conflict potential. In this context heightened interest of post-Soviet society to civil alternatives for global and posttraditional trends is ...
Yuri Mihaylovich Aksutin
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Social Capital, Rehabilitation, Tradition: Support for Restorative Justice in Japan and Australia [PDF]
, 2016 This paper investigates the attitudes and beliefs that the public hold about criminal behaviour in Japanese and Australian society, with a view to uncovering sources of resistance to, and support for, restorative justice. The study draws on a survey of 1,
Braithwaite, John +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Towards the Development of Innovative Strategies for Traditional Food Chains in the EU [PDF]
Organizations no longer compete as independent entities, but as chains (Christopher, 1998; Cox, 1999; Lambert, Cooper, 2000). Consequently, chain strategies became more important in creating competitive advantage (Vickery et al., 2003; Gunasekaran et al.,
Gellynck, Xavier +3 more
core +1 more source
Черты евроазиатских традиций в системе западного традиционализма в первой половине ХХ века [PDF]
, 2009 In the article author suggests version about presence of own set of traditions in classical Eurasian project. Notions of «traditionalism» and «conservatism» are considered in it.
Chanchikova, Julia T. +1 more
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Unassertability And The Appearance Of Ignorance [PDF]
, 2014 Whether it seems that you know something depends in part upon practical factors. When the stakes are low, it can seem to you that you know that p, but when the stakes go up it'll seem to you that you don't. The apparent sensitivity of knowledge to stakes
Pynn, Geoff
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Opportunism, Institutions and Moral Costs: the Socio-Cultural Dimension of the Underground Economy in Croatia 1995-1999 [PDF]
Since the causes and dynamics of the unofficial economy are inseparable from the sociocultural dimension, the authors analyze the dynamics of opportunism and (dis)trust in institutions in Croatia during the last half of the nineties. The analyses carried
Aleksandar Stulhofer, Ivan Rimac
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