Results 71 to 80 of about 9,117 (281)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Transitivity of Educational Environment of Modern Russian School as Psychological and Educational Problem

open access: yesНаучный диалог, 2018
The article is devoted to the problem of the functionality of the modern school educational environment, its readiness to solve its main social problems in the conditions of multiple and rapid transformations of material and social conditions of society.
A. D. Andreyeva
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Religion in the modern world: A political outlook [PDF]

open access: yesPharos Journal of Theology
The purpose of the study is to uncover the specifics of the importance of religion in today’s political system of Kazakhstan. The leading research methods used to address this issue include analysis, synthesis, deduction, induction, modelling, and the ...
Gulzhan Khussainova   +4 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

THE CHARACTERISTICS OF AN ABSTRACT SYSTEM FOR THE TRANSFER OF PROPERTY IN SOUTH AFRICAN LAW AS DISTINGUISHED FROM A CAUSAL SYSTEM

open access: yesPotchefstroom Electronic Law Journal, 2012
Two divergent systems are usually differentiated between when it comes to the way in which real rights are transferred from one person to another, namely abstract and causal systems.
PJW (Flip) Schutte
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Islamic Esotericism in the Bengali Bāul Songs of Lālan Fakir

open access: yesCorrespondences, 2019
This article makes use of the author’s field research as well as primary and secondary textual sources to examine Islamic esoteric content, as mediated by local forms of Bengali Sufism, in Bāul Fakiri songs.
Keith Cantú
doaj  

Traditionalist identity pattern in inheritance among Serbs in the North of Kosovo and Metohija: The case of the city of Kosovska Mitrovica [PDF]

open access: yesSociološki Pregled
Although numerous social changes taking place during socio-historical development have directly affected family life as a whole, many customs have been maintained and developed into socially acceptable rules of behaviour. In light of such considerations,
Marjanović Milica M.
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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