Results 61 to 70 of about 7,963 (303)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Slavia Meridionalis, 2017 The immured woman, Odysseus and Bulgarian Easter: Toncho Zhechev and the quest for a conservative myth This article reflects on Bulgarian Easter, or Bulgarian Passions, a 1975 book by the Bulgarian humanist Toncho Zhechev, once regarded in Communist ...
Grażyna Szwat-Gyłybowa
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Vekkelser i et samfunnsperspektiv [PDF]
Norsk Tidsskrift for Misjonsvitenskap, 2019 Revivals in a political-cultural perspective. The pietistic revivals in Norway, beginning with the lay preacher Hans Nielsen Hauge just before the 19th Century, were structured by the religious policy of the king of Denmark-Norway.
Bernt Torvild Oftestad
doaj
Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2019 Introduction. The introduction identifies one of the most important problems in the political history of Russia – the problem of determining and choosing the path of the long-term civilizational development in the aspect of liberal and conservative ...
Oleg V. Kuznetsov +2 more
doaj +1 more source
Serbia: A part of both the East and the West? [PDF]
Sociologija, 2003 The text comprises of two parts. The first is dealing with the basic historical preconditions for the formation of modern cultural patterns common to the largest part of the Serbian population and their relation towards those cultural patterns which ...
Lazić Mladen B.
doaj +1 more source
SSRN Electronic Journal, 2007 In important cases, the Supreme Court has limited the scope of "substantive due process" by reference to tradition, but it has yet to explain why it has done so. Due process traditionalism might be defended in several distinctive ways. The most ambitious defense draws on a set of ideas associated with Edmund Burke and Friedrich Hayek, who suggested ...
openaire +4 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source