Results 41 to 50 of about 9,117 (281)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Survival strategies of two changing societies’ customary consultative assemblies: The orahua of Nias and the kerapatan adaik of West Sumatra

Cogent Arts & Humanities
The discrepancy between customary governance systems and official village government systems can potentially result in conflict between indigenous communities and village officials, as evidenced in South Nias.
Ninawati Syahrul, Sastri Sunarti, Fatmahwati Fatmahwati, Atisah Atisah, Erli Yetti, Suryami Suryami, Agus Iswanto   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Traditionalism Rising [PDF]

Constitutional traditionalism is rising. From due process to free speech, religious liberty, the right to keep and bear arms, and more, the Court made clear in its 2021 term that it will follow a method that is guided by “tradition.” This paper is in ...
DeGirolami, Marc O.
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

IDENTITY PROJECTS IN THE DILEMMA OF MODERNITY AND TRADITION

Sakarya Üniversitesi İktisat Dergisi, 2012
For over a century, we have been accepting modernity as the basic data, and accordingly determining politics, and we are in the middle of a mental confusion, where traditionalism and modernism face, and even conflict at times.
Hasan Tutar
doaj  

The Dynamics of Islamic Law in the Balkans: Husein Dozo's Renewal Thoughts

Jurnal Madania
This article examines the dynamics of Islamic legal thought in the Balkans with a focus on the thoughts of a Muslim modernist and reformer Husein Dozo (1912-1982).
Yusdani Yusdani, Januariansyah Arfaizar, Ahmad Arifai   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Internalizarea tradiţionalismului de gen în adolescenţă: covariate ale atitudinii faţă de egalitatea de gen la elevii din clasele VIII-XII

Sociologie Românească, 2009
Gender traditionalism is one of the cultural traits of contemporary Romania which is one of the most patriarchal European societies. How is this cultural framework produced and reproduced in time is a major question for any attempt at promoting gender ...
Adrian Hatos
doaj  

Why Chinese “Society” is So Called: How Social and Managerial Discourse Caused the Choice of the Word at the Turn of the 19th and 20th Centuries

Дискурс
Introduction. The purpose of this article is to investigate the reasons for the choice of the   term “shehui” to designate the concept of “society” in China at the turn of the 19th and 20th   centuries.
E. V. Kremnyov
doaj   +1 more source