Results 51 to 60 of about 9,157 (281)
Introduction. The purpose of this article is to investigate the reasons for the choice of the term “shehui” to designate the concept of “society” in China at the turn of the 19th and 20th centuries.
E. V. Kremnyov
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Traditionalism involves the concept of a perennial philosophy, a central truth, underlying all major religions. Though little has been written about Swedish Traditionalism, consideration of the ideologies of figures such as Ivan Aguéli, Kurt Almqvist ...
Hammer, Olav; id_orcid
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The immured woman, Odysseus and Bulgarian Easter: Toncho Zhechev and the quest for a conservative myth This article reflects on Bulgarian Easter, or Bulgarian Passions, a 1975 book by the Bulgarian humanist Toncho Zhechev, once regarded in Communist ...
Grażyna Szwat-Gyłybowa
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Persistence of traditionalist value orientations in Serbia [PDF]
Systematic failures in attempts to modernize Serbian society during the past two centuries have led to the survival of traditionalist value orientations. The long period of Ottoman rule allowed patriarchal, warrior-tribal cultural patterns to persist and
Pešić Jelena
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Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

