Results 101 to 110 of about 1,436,329 (306)

A Different Kind of Wealth: Mapping a Baseline of African Community Foundations [PDF]

, 2012
This article focuses on how building on existing traditions of solidarity is challenging the conventions of mainstream ...
Barry Knight, Jenny Hodgson
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

L'efficacité des mécanismes de justice traditionnelle dans la résolution des conflits en Afrique : cas du Niger au XIXe siècle

Mu Kara Sani
Cet article vise à évaluer l’efficacité des mécanismes de justice traditionnelle au Niger dans leur capacité à résoudre les conflits au XIXe siècle. Cette étude permet de comprendre non seulement l’histoire du pays, mais aussi les interactions entre ...
Hassimou ALAKARBO
doaj  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Representation of the Bride’s Image in Paintings by Chuvash Artists

Polylinguality and Transcultural Practices
The image of the bride in world painting is the embodiment of youth and beauty. Reflecting the trends of the time and national ideals of femininity, the artists created a number of outstanding works.
Alina A. Malinina
doaj   +1 more source

Historical Schools of Economics: German and English [PDF]

This paper contrasts the German and English traditions of "Historical Economics" and explains their differences by positioning these two traditions in the specific institutional contexts in which they developed.Historical Economics, Historical School ...
Keith Tribe
core  

Semantics in Cultural Perspective Overview [PDF]

, 2018
The article was to aim to investigate the semantics overview based on the cultural perspective. The aim of semantics is to discover why meaning is more complex than simply the words formed in a sentence.  Culture is a word for the \u27way of life ...
Florence, K. (Karrie), Maria, F. (Franklin), Smith, V. (Virginia)   +2 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

REGIONAL AND ETHNIC VALUES, LANGUAGE AS A KEY FACTOR OF PRESERVING NATIONAL IDENTITY OF ETHNIC GROUPS, BASED ON THE TRADITIONS OF WESTERN GEORGIA – MARRIAGE

Humanities and Social Sciences
Ajara, a region in Georgia, is famous for its traditions and culture. The article explores the traditions of the Ajarian people that have mostly faded with time but still remain in some parts of Ajara.
Sopiko DUMBADZE, Manuchar LORIA
doaj   +1 more source

Animals in Christian and Muslim Thought [PDF]

, 2018
In this chapter, I shall offer a comparative exegesis and critical assessment of the Christian and Muslim views of animals. This chapter is divided into three parts.
Frayne, Carl Tobias
core