Results 51 to 60 of about 1,426,728 (307)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Les effets de la peine sur les proches des contrevenants : difficultés et discussion quant à leur problématisation lors de la détermination de la peine

open access: yesCriminologie, 2019
Cet article s’intéresse à la problématisation des effets de la peine sur les proches des personnes contrevenantes dans le contexte de la détermination de la peine.
Sophie de Saussure,
doaj   +1 more source

The United Methodist Church at 40: What Can We Hope For? [PDF]

open access: yes, 2009
The necessity we face for the future of Methodism is the re-invention of traditions. To re-invent traditions is to re-visit the past with all of its richness; to discern what in our tradition is most central to Christian faith; to analyze those parts of ...
Moore, Mary Elizabeth
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

The Transmission mechanisms of the position and Functions of Prophets in Abrahamic Religions [PDF]

open access: yesComparative Theology, 2013
Prophethood, possesses a profound significance in the Abrahamic religions. Prophets act as mediums, through whom the message of God is received and delivered to people, and thus fulfill two kinds of epistemological and Responsible functions: one related ...
Mohammad Reza Vasfi   +1 more
doaj   +1 more source

Comet and Meteorite Traditions of Aboriginal Australians

open access: yes, 2014
Of the hundreds of distinct Aboriginal cultures of Australia, many have oral traditions rich in descriptions and explanations of comets, meteors, meteorites, airbursts, impact events, and impact craters. These views generally attribute these phenomena to
AWR Bevan   +9 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

"Food Ethics and Religion" [PDF]

open access: yes, 2016
How does an engagement with religious traditions (broadly construed) illuminate and complicate the task of thinking through the ethics of eating? In this introduction, we survey some of the many food ethical issues that arise within various religious ...
Doggett, Tyler, Halteman, Matthew C.
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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