Results 81 to 90 of about 1,436,329 (306)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The American Religious Landscape and the 2004 Presidential Vote: Increased Polarization [PDF]

open access: yes, 2005
Presents findings from a post-election survey conducted in November and December 2004.
Corwin E. Smidt   +3 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Secular and the Sacred: Complementary And/or Conflictual? [PDF]

open access: yes, 2017
The issue of the relation of the sacred to the secular has become paramount in virtually every country in the world. From church-state relations in the US, with the debates around abortion and same-sex marriage, to the vitriolic discussions in France ...
Akhlaq, Sayed Hassan Hussaini   +1 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

PERSIAN DANCE: TRADITIONS AND MODERNITY

open access: yesКонцепт: философия, религия, культура, 2019
This article attempts to explore Persian dances in order to determinate its national identity. The authors refer to the semantic core of the lexemes that express this phenomenon, give a brief outline of the genesis and evolution of this traditional ...
A. V. Berezina, M. G. Delinad
doaj   +1 more source

Meteoritics and cosmology among the Aboriginal cultures of Central Australia

open access: yes, 2011
The night sky played an important role in the social structure, oral traditions, and cosmology of the Arrernte and Luritja Aboriginal cultures of Central Australia. A component of this cosmology relates to meteors, meteorites, and impact craters.
Hamacher, Duane W.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

East-meets-West: How the Dhammapada Influenced the New Thought Movement [PDF]

open access: yes, 2018
New Thought teachings are based on a variety of pre-existing traditions as well as on information new to the human consciousness. While the exact source of specific New Thought concepts is unclear, evidence suggests that the movement benefited from ...
Anama-Green, Chris
core  

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