Results 101 to 110 of about 2,581,817 (334)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Mode of the Past or Promise for the Future? Cycling in China and the Sustainability Challenge, 1955–Present

Zeithistorische Forschungen, 2017
Since the 1950s, cycling policy in China has gone through three phases: from active encouragement (1955–1994) and systematic discouragement (1994–2008) to neglect and ambivalence (since the 2010s).
Ruth Oldenziel
doaj   +1 more source

Traffic Speed Report No. 124 : Traffic Report

, 1991
This report is an analysis of spot speed observations made during the 1990 summer months of May, June, July and August. All observations were made of free-flowing vehicles on level, tangent sections of rural and urban highways under favorable conditions. All observations were made during daylight hours.
Cochran, David L., Genda, Donald W.
openaire   +4 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Fluorescent Nanodiamonds Based Theranostic Platform for pH‐Sensitive Drug Delivery and Quantum Sensing

Advanced Functional Materials, EarlyView.
A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu, Siyu Fan, Yue Zhang, Willem Woudstra, Thomas Mulder, Laurens Boscher Navarro, Jur van Dijken, Katja Loos, Romana Schirhagl   +8 more
wiley   +1 more source

Phase Change Material‐Driven Tunable Metasurface for Adaptive Terahertz Sensing and Communication in 6G Perceptive Networks

Advanced Functional Materials, EarlyView.
This study explores the benefits of metasurfaces made from functional materials, highlighting their ability to be adapted and improved for various high‐frequency applications, including communications and sensing. It first demonstrates the potential of these functional material‐based metasurfaces to advance the field of sub‐THz perceptive networks ...
Yat‐Sing To, Jiachen Du, Cyril Decroze, Laure Huitema, Aurelian Crunteanu, Hang Wong   +5 more
wiley   +1 more source

Enhanced motorway capacity estimation considering the impact of vehicle length on the fundamental diagram

IET Intelligent Transport Systems
The ability to understand the underlying fundamentals of traffic flow behaviour facilitates improved planning and decision‐making for road operators.
Erik Giesen Loo, Robert Corbally, Lewis Feely, Andrew O'Sullivan   +3 more
doaj   +1 more source

Estimation of Traffic Matrices for LRD Traffic

, 2012
The estimation of traffic matrices in a communications network on the basis of a set of traffic measurements on the network links is a well-known problem, for which a number of solutions have been proposed when the traffic does not show dependence over time, as in the case of the Poisson process.
P. L. Conti, DE GIOVANNI, LIVIA, M. Naldi   +2 more
openaire   +3 more sources

Ice Lithography: Recent Progress Opens a New Frontier of Opportunities

Advanced Functional Materials, EarlyView.
This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang, Gwendoline A. E. Anand, Rubaiyet Haque, Dylan A. Chiaro, Mona Sharma, Andrew R. Williams, Frank Niklaus, Daryl W. Yee, Gavin M. King, Anpan Han   +9 more
wiley   +1 more source

Seasonal Variability and Trends of PM10 and PM2.5 Particulate Matter Pollution in Warsaw: A Multi-Year Analysis

Environmental Protection and Natural Resources
The article examines the temporal variability and seasonal trends of PM10 and PM2.5 particulate matter pollution in Warsaw over six years from 2016 to 2021.
Starzomska Aleksandra, Strużewska Joanna   +1 more
doaj   +1 more source