Results 81 to 90 of about 3,288,100 (328)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The accumulation of metals in Polygonum aviculare L. in area of the Kraljevo city [PDF]

Kragujevac Journal of Science, 2014
Elevated heavy metal concentrations cause environmental pollution. Our study examines the content of heavy metals (Pb, Ni, Mn, Fe and Cu) in the aboveground parts of Polygonum aviculare L.
Radulović Monika, Stanković Milan S., Simić Zoran, Radaković Miloš, Topuzović Marina   +4 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Effects of Flashing Brake Lights on Drivers’ Brake Reaction Time and Releasing Accelerator Gas Pedal Time

Health in Emergencies & Disasters Quarterly, 2019
Background: Drivers play a crucial role in accidents. By paying attention to brake lights, a driver may find out about danger and react adequately. Rear-end collision accidents are caused by the driver’s inattention or slow reaction.
Mohammad Sadegh Sohrabi
doaj  

APPLICATION OF FUZZY LOGIC TO TRAFFIC SIGNAL CONTROL UNDER MIXED TRAFFIC CONDITIONS [PDF]

, 2007
Traffic signal control is commonly used at road intersections to minimise vehicular delay. Fixed time control shows good results in conditions where there is a little fluctuation in traffic demand, however in time-varying traffic
Yulianto, Budi
core  

Criterion for traffic phases in single vehicle data and empirical test of a microscopic three-phase traffic theory

, 2005
A microscopic criterion for distinguishing synchronized flow and wide moving jam phases in single vehicle data measured at a single freeway location is presented.
Andreas Hiller, Banks J, Boris S Kerner, Bovy P H L, Fukui M Sugiyama Y Schreckenberg M Wolf D E, Gartner N H, Gurusinghe G S Nakatsuji T Azuta Y Ranjitkar P Tanaboriboon Y, Helbing D, Hoogendoorn S P Luding S Bovy P H L Schreckenberg M Wolf D E, Jiang R, Kerner B S, Kerner B S, Kerner B S, Kerner B S, Kerner B S Klenov S L Hiller A, Knospe W, Koshi M Iwasaki M Ohkura I Hurdle V F, Luttinen T, Mahmassani H S, Nagatani T, Sergey L Klenov, Tilch B Helbing D Helbing D Herrmann H J Schreckenberg M Wolf D E, Wagner P Fukui M Sugiyama Y Schreckenberg M Wolf D E, Wagner P Lubashevsky I   +23 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Efficiency and Stability Ratios of the Transport Corporation Business

Promet (Zagreb), 2012
Multidisciplinary character of traffic science in a widersense and science abouttransp01t in a narrower sense stipulatethe definition of semantic relation between the terms "transpori"and "traffic", as well as the meaning of conventional,combined and ...
Ratko Zelenika, Katarina Toković
doaj   +1 more source