Results 111 to 120 of about 3,312,575 (362)
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock +8 more
wiley +1 more source
Speed Adaptation in Urban Road Network Management
Transport and Telecommunication, 2016 Various forecasting schemes have been proposed to manage traffic data, which is collected by videos cameras, sensors, and mobile phone services. However, these are not sufficient for collecting data because of their limited coverage and high costs for ...
Raiyn Jamal
doaj +1 more source
Advanced Engineering Materials, EarlyView.This study explores the effects of pixel size and spacing when fabricating electroluminescent (EL) multipixel displays. COMSOL simulations identify the impact of pixel dimensions and spacing on electric field distribution and lighting efficiency. Flexible, high‐resolution EL pixel arrays are reverse offset printed, achieving a 96% reduction in pixel ...
Huanghao Dai +3 more
wiley +1 more source
Legal measures for achieving sustainable traffic in European cities [PDF]
Urbani Izziv, 2000 The article presents the LEDA research project that dealt with legal measures needed to achieve sustainable traffic in European cities. The participants in the project gathered and analysed operational legal measures in European cities.
Aljaž Plevnik
doaj
Road traffic noise and health-related quality of life: A cross-sectional study
Noise and Health, 2013 Evidence is emerging linking environmental noise to health problems. Noise can affect health directly and indirectly: For example, noise sensitivity moderates the effects of noise annoyance, which in turn mediates the effects of noise exposure.
David Welch +4 more
doaj +1 more source
Characterization of P2P IPTV Traffic: Scaling Analysis
, 2007 P2P IPTV applications arise on the Internet and will be massively used in the future. It is expected that P2P IPTV will contribute to increase the overall Internet traffic.
Fourmaux, Olivier +2 more
core
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Advanced Functional Materials, EarlyView.Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu +6 more
wiley +1 more source
Cycling as Recreation and Transportation Necessity
Promet (Zagreb), 2012 This paper considers the actual problematic of cycling intraffic. It emphasises possible bigger role of the bicycle in urbancentres as transport device that could be one of the ways of reducingtraffic jams.
Igor Bogović
doaj +1 more source
Advanced Functional Materials, EarlyView.The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang +9 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2017 Single point mutations or variations in the expression of the gene encoding the neuronal glycoprotein M6a have been associated with psychiatric disorders such as Alzheimer’s disease, depression and schizophrenia.
Micaela D. Garcia +4 more
doaj +1 more source