Results 61 to 70 of about 2,581,817 (334)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
An Open-Source Microscopic Traffic Simulator
, 2010 We present the interactive Java-based open-source traffic simulator available at www.traffic-simulation.de. In contrast to most closed-source commercial simulators, the focus is on investigating fundamental issues of traffic dynamics rather than ...
Kesting, Arne, Treiber, Martin
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Efficiency and Stability Ratios of the Transport Corporation Business
Promet (Zagreb), 2012 Multidisciplinary character of traffic science in a widersense and science abouttransp01t in a narrower sense stipulatethe definition of semantic relation between the terms "transpori"and "traffic", as well as the meaning of conventional,combined and ...
Ratko Zelenika, Katarina Toković
doaj +1 more source
APPLICATION OF FUZZY LOGIC TO TRAFFIC SIGNAL CONTROL UNDER MIXED TRAFFIC CONDITIONS [PDF]
, 2007 Traffic signal control is commonly used at road intersections to minimise vehicular delay. Fixed time control shows good results in conditions where there is a little fluctuation in traffic demand, however in time-varying traffic
Yulianto, Budi
core
Structural Analysis of Network Traffic Matrix via Relaxed Principal Component Pursuit
, 2012 The network traffic matrix is widely used in network operation and management. It is therefore of crucial importance to analyze the components and the structure of the network traffic matrix, for which several mathematical approaches such as Principal ...
Dong, Xiaowen +4 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Traffic simulation of broadband LEO constellation satellite communication system
Dianzi Jishu Yingyong, 2019 Due to the rapid development of small satellite technology，and the advantages of low earth orbit satellite(LEO) with low delay and low propagation loss as compared with the traditional geosynchronous orbit satellite(GEO), the broadband LEO constellation ...
Xu Jun, Lu Wei, Zhang Gengxin
doaj +1 more source
Atmosphere, 2020 One of the main environmental problems we are currently facing is air pollution. Air quality models calculate how much pollution is emitted and dispersed into the atmosphere.
Alejandro Marulanda Tobón +3 more
doaj +1 more source