Results 91 to 100 of about 10,142,694 (298)

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Independence-Monmouth Traffic Safety Management Program (TSMP)

, 1981
Cover letter title: Independence-Monmouth Traffic Safety Management Program (TSMP).At head of title: Preliminary."July 1981.""OTSC Project #81-02-5-609."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents ...

core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Automated Traffic Control System for Emergency Services [PDF]

, 2015
This project aims at creating an effective automated traffic control system to prevent ambulances/emergency service vehicles from getting caught up in traffic, there by decreasing hindrances to vital services both in regular and critical situations.
M Prasanth
core  

Optimal Configuration and Path Planning for UAV Swarms Using a Novel Localization Approach

Applied Sciences, 2018
In localization estimation systems, it is well known that the sensor-emitter geometry can seriously impact the accuracy of the location estimate. In this paper, time-difference-of-arrival (TDOA) localization is applied to locate the emitter using ...
Weijia Wang, Peng Bai, Hao Li, Xiaolong Liang   +3 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Lowering traffic without sacrificing performance in networked control systems

, 2011
In Networked Control Systems (NCS), the amount of control data exchanged between sensors, controllers and actuators nodes highly depends on the control performance specifications given to each networked control loop.
Martín Rull, Enric Xavier, Manel Velasco, Yépez Castillo, José Gregorio, Enric X. Martin, Pau Marti, Jose Yepez, Velasco García, Manel, Martí Colom, Pau   +7 more
core   +1 more source

Hierarchical Target Tracking for Unmanned Aerial Vehicle Swarms with Distributed Optimization and Affine Control

Drones
Target tracking of unmanned aerial vehicle (UAV) swarms remains a significant challenge due to highly maneuverable target swarms and complex environments.
Han Wang, Xiaolong Liang, Jiaqiang Zhang, Yueqi Hou, Aiwu Yang   +4 more
doaj   +1 more source

A Short Turning Strategy for Train Scheduling Optimization in an Urban Rail Transit Line: The Case of Beijing Subway Line 4

Journal of Advanced Transportation, 2018
In urban rail transit systems, train scheduling plays an important role in improving the transport capacity to alleviate the urban traffic pressure of huge passenger demand and reducing the operation costs for operators.
Miao Zhang, Yihui Wang, Shuai Su, Tao Tang, Bin Ning   +4 more
doaj   +1 more source