Results 151 to 160 of about 113,285 (311)
Statistical computation for extreme bridge traffic load effects
, 2012 Eighth International Conference on Computational Structures Technology, Las Palmas de Gran Canaria, Spain, from 12 to 15 September 2006The maintenance of highway infrastructure constitutes a major expenditure in many countries.
O\u27Brien, Eugene J. +2 more
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O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer
Advanced Science, EarlyView.This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu +10 more
wiley +1 more source
Adaptive traffic signal control using approximate dynamic programming
, 2009 This thesis presents a study on an adaptive traffic signal controller for real-time operation. An approximate dynamic programming (ADP) algorithm is developed for controlling traffic signals at isolated intersection and in distributed traffic networks.
Chen Cai, Cai, C.
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A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
Advanced Science, EarlyView.This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Stochastic user equilibrium assignment with traffic-responsive signal control [PDF]
This paper considers the Stochastic User Equilibrium (SUE) assignment problem for a signal-controlled network in which intersection control is flow-responsive.
Claudio Meneguzzer
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Advanced Science, EarlyView.An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang +7 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Conception of the cognitive engineering design problem
, 1998 Cognitive design, as the design of cognitive work and cognitive tools, is predominantly a craft practice that currently depends on the experience and insight of the designer. However, the emergence of a discipline of cognitive engineering promises a more
Long, J, Dowell, J
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Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Traffic data logging system for red-running violation studies
, 2001 This paper illustrates the use of a custom-modified logging system to collect field data at signalised junctions to study red-running violations. Operational and memory requirements of the system in terms of detecting stationary traffic and monitoring ...
Lum, Kit Meng, Wong, Yiik Diew
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