Results 131 to 140 of about 113,285 (311)

SCDOT traffic signal design guidelines 2021 [PDF]

open access: yes, 2020
The purpose of the South Carolina Department of Transportation Traffic Signal Design Guidelines is to establish guidance, procedures and specifications that promote uniformity in the design of traffic signals.
South Carolina Department of Transportation. Traffic Engineering
core  

Passenger Flow Simulation Model for Urban Rail Transit Stations Based on Multipotential Fields in Three-Dimensional Space

open access: yesJournal of Advanced Transportation
The spatial and temporal rules governing passenger flow in urban rail transit (URT) stations are complex, and simulation modeling and analysis of passenger flow distribution in stations are very important in regard to scientifically organizing and ...
Lianbo Deng   +4 more
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Towards Robust Traffic Engineering in IP Networks [PDF]

open access: yes, 2007
To deliver a reliable communication service it is essential for the network operator to manage how traffic flows in the network. The paths taken by the traffic is controlled by the routing function.
Gunnar, Anders
core  

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Multicriteria cruise control design considering geographic and traffic conditions

open access: yes, 2013
The paper presents the design of cruise control systems considering road and traffic information during the design of speed trajectories. Several factors are considered such as road inclinations, traffic lights, preceding vehicles, speed limits, engine ...
Varga, István   +3 more
core   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

The Influence of Correclation on the Extreme Traffic Loading of Bridges

open access: yes, 2012
Bridge Maintenance, Safety and Management (IABMAS'10) the Fifth International IABMAS Conference, Philadelphia, USA, 11-15 July 2010Accurate traffic loading models based on measured data are essential for the accurate assessment of existing bridges ...
O\u27Brien, Eugene J.   +3 more
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

An Investigation into Traffic Turning Movement at Jibowu [PDF]

open access: yes
This paper aims at understanding the behavioral pattern of traffic at Jibowu intersection with a view of using the results obtained as a model for understudying traffic movement at similar intersections in the Lagos metropolis.
S.A. Oke, S. I. Oni
core  

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