Results 121 to 130 of about 113,285 (311)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

The Impact of a Bump on the Response of a Bridge to Traffic

, 2012
The Twelfth International Conference on Civil, Structural and Environmental Engineering Computing, Funchal, Madeira, Portugal, 1-4 September 2009There are numerous studies on the dynamic amplification factors caused by traffic flow on a bridge.
O\u27Brien, Eugene J., O'Brien, Eugene J., González, Arturo, Cantero, Daniel   +3 more
core  

Application of multi-beam line model based on computational geometry

AIP Advances
This study focuses on the application of the multibeam bathymetric system in modern marine surveying, which has significant advantages in ocean engineering, geology exploration, and channel measurement.
Yuting Zhang, Zaibin Chang, Yaqin Qiao, Wenjuan Liu   +3 more
doaj   +1 more source

Algorithms for ribosome traffic engineering and their potential in improving host cells' titer and growth rate. [PDF]

Sci Rep, 2020
Zur H, Cohen-Kupiec R, Vinokour S, Tuller T.   +3 more
europepmc   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Objectives, stimulus and feedback in signal control of road traffic

, 2004
This article identifies the prospective role of a range of intelligent transport systems technologies for the signal control of road traffic. We discuss signal control within the context of traffic management and control in urban road networks and then ...
Heydecker, BG
core  

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Remote Airport Tower Operation with Augmented Vision Video Panorama HMI

, 2006
In this paper the initial results of the DLR project Remote Airport Tower Operation Research (RapTOr) are described. Within this project an augmented vision video panorama system and a corresponding HMI is developed for remote surface movement management
Schmidt, Markus, Fürstenau, Norbert, Werther, Bernd, Rudolph, Michael   +3 more
core  

A duplex transform heterogeneous feature fusion network for road segmentation

Scientific Reports
Detecting roads in automatic driving environments poses a challenge due to issues such as boundary fuzziness, occlusion, and glare from light. We believe that two factors are instrumental in addressing these challenges and enhancing detection performance:
Zhiyang Guo, Xing Hu, Jiejia Wang, XiaoYu Miao, MengTeng Sun, HuaiWei Wang, XueYing Ma   +6 more
doaj   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source