Results 81 to 90 of about 271,388 (282)

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

RESEARCH OF ENGINEERING TRAFFIC IN COMPUTER UZ NETWORK USING MPLS TE TECHNOLOGY

Science and Transport Progress, 2015
Purpose. In railway transport of Ukraine one requires the use of computer networks of different technologies: Ethernet, Token Bus, Token Ring, FDDI and others. In combined computer networks on the railway transport it is necessary to use packet switching technology in multiprotocol networks MPLS (MultiProtocol Label Switching) more effectively.
openaire   +3 more sources

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Research on Risk Factors Affecting High-Speed Railway Delays in China Based on Association Rules

Promet (Zagreb)
This study aimed to investigate the contributing factors to high-speed railway (HSR) delays and their interdependency in China. A total of 420 records of high-speed railway delays in China were collected, and 15 risk factors related to high-speed railway
Aidi WANG, Yingying XING, Hong LANG, Hongwei WANG, Jian John LU   +4 more
doaj   +1 more source

Technology and application of intelligent driving based on visual perception

CAAI Transactions on Intelligence Technology, 2019
The camera is one of the important sensors to realise the intelligent driving environment. It can realise lane detection and tracking, obstacle detection, traffic sign detection, identification and discrimination and visual simultaneous localisation and ...
Xinyu Zhang, Hongbo Gao, Guotao Xie, Buyun Gao, Deyi Li   +4 more
doaj   +1 more source

Vehicle Fuel Consumption Prediction Method Based on Driving Behavior Data Collected from Smartphones

Journal of Advanced Transportation, 2020
Transportation is an important factor that affects energy consumption, and driving behavior is one of the main factors affecting vehicle fuel consumption. The purpose of this paper is to improve fuel consumption monitoring databases based on mobile phone
Ying Yao, Xiaohua Zhao, Chang Liu, Jian Rong, Yunlong Zhang, Zhenning Dong, Yuelong Su   +6 more
doaj   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Deriving Sight Distance on a Compound Sag and Circular Curve in a Three Dimensional Space

International Journal of Transportation Science and Technology, 2012
Insufficient roadway sight distance (SD) may become a contribution factor to traffic collisions or other unsafe traffic maneuvers. The sight distance (SD) for a two-dimensional (2-d) sag or circular curve has been addressed in detail in various traffic ...
Chiu Liu, PhD, PE, PTOE, Zhongren Wang, PhD, PE, TE   +1 more
doaj   +1 more source