Results 91 to 100 of about 6,793,000 (262)
Advanced Science, EarlyView.A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv +16 more
wiley +1 more source
Parallel Traffic Flow Simulation of Freeway Networks, Phase 1: Final Report
, 1994 Numerical methods for solving simple macroscopic traffic flow continuum models have been studied and efficiently implemented in traffic simulation codes.
Rhee, Choong-Yul +2 more
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Exploratory learning for wireless networking [PDF]
, 2011 This dissertation highlights the importance of computer networking education and the challenges in engaging and educating students. An exploratory learning approach is discussed with reference to other learning models and
Sturgeon, Thomas
core +2 more sources
Advanced Science, EarlyView.In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao +12 more
wiley +1 more source
Advanced Science, EarlyView.A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang +7 more
wiley +1 more source
Passive Online RTT Estimation for Flow-Aware Routers Using One-Way Traffic
, 2010 International audienceWith the introduction of new generation high speed routers, and with the help of "flow-aware" traffic management, it becomes possible to improve the Quality of Service for users as well as the network efficiency for ISPs. An example
Carra, Damiano +11 more
core +1 more source
Resource and Traffic Management Techniques for Performance Optimization in Wireless Mesh Networks [PDF]
, 2010 Since Internet was born, it has steadily evolved. New devices, new needs, new applications, new protocols, and this evolution is not going to slow down in the near future. As a result of the introduction and standardization of wireless access technology,
D'Elia, Francesco Paolo
core +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
Advanced Science, EarlyView.This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
The development of decision support models for European air traffic flow management [PDF]
Congestion severely affects air traffic in the US and Europe. To protect air traffic controllers from overloads a planning activity, Air Traffic Flow Management (ATFM), emerged during the 1970s.
De Matos, Paula Alexandra Leal
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Performance of car following behaviour in microscopic traffic flow models [PDF]
, 2004 Microscopic simulation models are becoming increasingly important tools in modelling transport systems. They are applied in simulation programs for transport planning, traffic forecasting and advanced vehicle control and safety systems (AVCSS).
Brockfeld, Elmar +2 more
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