Results 81 to 90 of about 6,793,000 (262)

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Parallel Traffic Flow Simulation of Freeway Networks: Phase 2

open access: yes, 1997
Explicit and implicit numerical methods for solving simple macroscopic traffic flow continuum models have been studied and efficiently implemented in traffic simulation codes in the past.
Chronopoulos, Anthony
core  

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Hybrid flow data center network architecture design and analysis

open access: yes, 2017
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2017.Cataloged from PDF version of thesis.Includes bibliographical references (pages 127-132).In this thesis, we propose a hybrid flow ...
Huang, Henna Priscilla
core  

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Traffic classification: Packet-, flow-, and application-based approaches

open access: yes, 2010
Traffic classification is a very important mathematical and statistical tool in communications and computer networking, which is used to find average and statistical information of the traffic passing through certain pipe or hub.
Sasan Adibi (11629147)
core  

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Self-Organizing Traffic at a Malfunctioning Intersection [PDF]

open access: yes
Traffic signals and traffic flow models have been studied extensively in the past and have provided valuable insights on the design of signalling systems, congestion control, and punitive policies. This paper takes a slightly different tack and describes
Sugata Mitra, Sujai Kumar
core  

Introduction to Computer Networking and Hardware Concepts

open access: yes
This chapter provides an introduction to computer networking and hardware concepts and highlights the use of software and hardware tools as an aid to enhance teaching and learning computer networking and hardware fundamentals.
Nurul I. Sarkar
core   +1 more source

Latent Heat of a Traffic Model

open access: yes, 2013
We have studied the optimal velocity model (Bando et al., Jpn J Indust Appl Math 11:203, 1994; Phys Rev E 51:1035, 1995; J Phys I Fr 5:1389, 1995) for highway traffic. On a microscopic level, traffic flow is described by Bando's optimal velocity model in
Mahnke, Reinhard,   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy