Results 31 to 40 of about 6,793,000 (262)

A Kalman filtering approach to traffic flow estimation in computer networks

IFAC-PapersOnLine, 2018
Abstract In this paper, data-based estimation of traffic flows in computer networks is dealt with. The knowledge of the traffic matrix, containing the values of flows among the nodes in a computer network, could be very useful in many aspects of network management, like capacity planning, traffic load distribution and anomaly detection.
Pozzi, G., Formentin, S., Lluka, P., Bittanti, S.   +3 more
openaire   +2 more sources

Predicting Traffic Flow with Federated Learning and Graph Neural with Asynchronous Computations Network

Array
Real-time traffic flow prediction holds significant importance within the domain of Intelligent Transportation Systems (ITS). The task of achieving a balance between prediction precision and computational efficiency presents a significant challenge.
Muhammad Yaqub, Shahzad Ahmad, Malik Abdul Manan, Muhammad Salman Pathan, Lan He   +4 more
openaire   +6 more sources

A Novel Traffic Scheduling Algorithm for Multi-CQF Using Mixed Integer Programming and Variable Neighborhood Search Genetic Algorithm in Time-Sensitive Networking

Sensors
Time-Sensitive Networking (TSN) is an advance Ethernet paradigm designed to provide low delay, low jitter, and deterministic transmission time. The Cycling Queuing and Forwarding (CQF) mechanism is introduced in TSN as a scheduler to achieve precise ...
Cheng Wang, Zhiquan Lin, Yuhao Zhao, Fen Hu, Zhan Huan   +4 more
doaj   +1 more source

On the LRD of the Aggregated Traffic Flows in High-Speed Computer Networks

, 2021
This paper studies and analyses the behavior of the Long-Range Dependence in network traffic after classifying traffic flows in aggregated time series. Following Differentiated Services architecture principles, the generic Quality of Service applications that requirements and use the transport control protocol, a basic classification criterion of time ...
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Machine Learning-Based Cyberattack Detection in NFV: Performance, Efficiency and Explainability Analysis

Applied Sciences
Network Function Virtualization (NFV) is a novel concept in computer networking that enhances scalability and flexibility in network services. Its increasing complexity and highly dynamic nature challenge reliable and efficient cyberattack detection ...
Sara Fileković, Emine Yaman
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source