Results 101 to 110 of about 1,051,957 (289)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

SMB-YOLOv5: A Lightweight Airport Flying Bird Detection Algorithm Based on Deep Neural Networks

IEEE Access
Birds pose a serious threat to the safe operation of aircrafts. Existing object detection methods have achieved good results for big and medium instances; however, for small flying bird instances, drawbacks such as slow speed, low accuracy, and large ...
Haijun Liang, Xiangwei Zhang, Jianguo Kong, Zhiwei Zhao, Kexin Ma   +4 more
doaj   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

Solving UAV 3D Path Planning Based on the Improved Lemur Optimizer Algorithm

Biomimetics
This paper proposes an Improved Lemur Optimization algorithm (ILO), which combines the advantages of the Spider Monkey Optimization algorithm, Simulated Annealing algorithm, and Lemur Optimization algorithm.
Haijun Liang, Wenhai Hu, Ke Gong, Jie Dai, Lifei Wang   +4 more
doaj   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Spatial dynamics of transport accessibility and regional efficiency in the Yangtze River Delta Urban Agglomeration

Scientific Reports
Transport accessibility is crucial for defining urban clusters and evaluating a region's centrality and connectivity. To foster equitable growth in urban conglomerates, it is crucial to understand the relationship between transport accessibility and ...
Yafei Li, Meijun Teng, Yuxi Liu
doaj   +1 more source

Graph-Enhanced Deep Learning With Character Similarity Mining for Automated NOTAM Correction in Aviation Systems

IEEE Access
As the number of Notices to Airmen (NOTAMs) has increased exponentially, the existing manual processing methods have become increasingly inefficient and error-prone.
Bing Dong, Haoran Yao, Chuang Luo, Ruichao Yang, Ziyue Wang   +4 more
doaj   +1 more source

Air traffic control by distributed management in a MLS environment [PDF]

The microwave landing system (MLS) is a technically feasible means for increasing runway capacity since it could support curved approaches to a short final.
Hart, S., Kreifeldt, J. G., Parkin, L.
core   +1 more source

Light‐Harvesting Photothermal Hotspots Enabled by NIR Scattering‐Absorption Coupling

Advanced Science, EarlyView.
By coupling the broadband scattering of nanodiamonds with the plasmonic absorption of gold nanostars, this work proposes a novel strategy for the active modulation of photon transport. This strategy creates localized photothermal hotspots in turbid media and achieves a supra‐additive heating efficiency, thereby providing a universal platform for low ...
Zebin Wu, Changming Bao, Pengyu Zhang, Tao Ding, Weiming Lin, Haodong Li, Wenjian Luo, Xizhi Deng, Hao Wang, Guanle Li, Hongyue Hu, Ye Wang, Dawei Jiang, Yu Zhang, Sisi Jia, Nan Zhang, Min Ke, Le Liang   +17 more
wiley   +1 more source

Traffic Management in IoT Backbone Networks Using GNN and MAB with SDN Orchestration. [PDF]

Sensors (Basel), 2023
Guo Y, Wang Y, Khan F, Al-Atawi AA, Abdulwahid AA, Lee Y, Marapelli B.   +6 more
europepmc   +1 more source