Results 71 to 80 of about 1,051,957 (289)

An Improved Spider Wasp Optimizer for UAV Three-Dimensional Path Planning

Biomimetics
This paper proposes an Improved Spider Wasp Optimizer (ISWO) to address inaccuracies in calculating the population (N) during iterations of the SWO algorithm.
Haijun Liang, Wenhai Hu, Lifei Wang, Ke Gong, Yuxi Qian, Longchao Li   +5 more
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Network Resilience and Rehabilitation Strategies for an Airport Movement Area Considering Traffic Flow and Road Class

International Journal of Aerospace Engineering
In this study, we propose an improved betweenness centrality (FDBC) algorithm to identify vulnerabilities in airport field operations, assist controllers in formulating emergency response strategies, and enhance the safety resilience of the maneuvering ...
Ruiling Mou, Rui Kang
doaj   +1 more source

Multifactor-coupled study on freeze-thaw forces of rocks in cold regions

Frontiers in Earth Science
This study delves into the mechanical properties of steep and rocky slopes subjected to long-term freeze-thaw actions. Considering the unique climatic conditions in cold regions, especially the significant impact of seasonal and diurnal temperature ...
Yonghui Zhao, Kun Hu, Deming Han, Yongxian Lang, Lin Zhang   +4 more
doaj   +1 more source

Air Traffic Management Safety Challenges

, 2007
The primary goal of the Air Traffic Management (ATM) system is to control accident risk. ATM safety has improved over the decades for many reasons, from better equipment to additional safety defences.
Brooker, Peter
core  

CARBOTRAF: A decision Support system for reducing pollutant emissions by adaptive traffic management [PDF]

, 2015
Traffic congestion with frequent “stop & go” situations causes substantial pollutant emissions. Black carbon (BC) is a good indicator of combustion-related air pollution and results in negative health effects.
Beckx, C, Dahlem, D, Elen, B, Hu, J, Kouwijzer, K, Litzenberger, M, Marcinek, M, Mascia, M, Mills, J, North, R, Theunis, J, van Poppel, M, Vranckx, S   +12 more
core  

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Global Modeling and Prediction of Computer Network Traffic [PDF]

, 2009
We develop a probabilistic framework for global modeling of the traffic over a computer network. This model integrates existing single-link (-flow) traffic models with the routing over the network to capture the global traffic behavior.
Michailidis, George, Stoev, Stilian A., Vaughan, Joel   +2 more
core  

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source