Results 51 to 60 of about 81,822 (262)

Edge Computing for Effective and Efficient Traffic Characterization

Sensors, 2023
Traffic flow analysis is essential to develop smart urban mobility solutions. Although numerous tools have been proposed, they employ only a small number of parameters.
Asif Khan, Khurram S. Khattak, Zawar H. Khan, Thomas Aaron Gulliver, Abdullah   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Adaptive Input Sampling: A Novel Approach for Efficient Object Detection in High Resolution Traffic Monitoring Images

IEEE Access
Real-time traffic monitoring based on artificial intelligence (AI) models is essential for efficient transportation management, but it faces significant computational challenges, particularly when processing high-resolution video footage.
Tewodros Syum Gebre, Eden Tsehaye Wasehun, Freda Elikem Dorbu, Gazali Oluwasegun Agboola, Ali Karimoddini, Leila Hashemi-Beni   +5 more
doaj   +1 more source

Monitoring Traffic Optimization in a Smart Grid

IEEE Transactions on Industrial Informatics, 2017
The emergence of microgeneration systems steadily increases, and it raises concerns regarding their impact on the power grid. It is, therefore, crucial to efficiently integrate them into future smart grid architectures, as there is not any standard way to monitor production units. Moreover, current data collection systems are simple and do not consider
Guillaume Habault, Maxime Lefrançois, François Lemercier, Nicolas Montavont, Periklis Chatzimisios, Georgios Z. Papadopoulos   +5 more
openaire   +3 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Distributed Acoustic Sensing for Road Traffic Monitoring: Principles, Signal Processing, and Emerging Applications

Infrastructures
With accelerating urbanization and the exponential growth in vehicle populations, high-precision traffic monitoring has become indispensable for intelligent transportation systems (ITSs).
Jingxiang Deng, Long Jin, Hongzhi Wang, Zihao Zhang, Yanjiang Liu, Fei Meng, Jikai Wang, Zhenghao Li, Jianqing Wu   +8 more
doaj   +1 more source

Virtual Induction Loops Based on Cooperative Vehicular Communications

Sensors, 2013
Induction loop detectors have become the most utilized sensors in traffic management systems. The gathered traffic data is used to improve traffic efficiency (i.e., warning users about congested areas or planning new infrastructures).
Maria Calderon, Carlos J. Bernardos, Marco Gramaglia   +2 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source