Results 41 to 50 of about 34,991 (266)
MathematicsThis study looks at how travelers move between MADINA and JEDDA, using the UPPAAL Stratego tool to tackle the complexities of urban mobility. As cities grow, effective transportation planning becomes more challenging.
Moez Krichen, Ahmed Harbaoui
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Future InternetThis study examines the integration of the Internet of Vehicles (IoV) and blockchain as tools to optimize traffic management in Roll-on/Roll-off (Ro-Ro) terminals within the Spanish port system.
Nicoletta González-Cancelas +2 more
doaj +1 more source
Sensors, 2023 With the continued rapid growth of urban areas, problems such as traffic congestion and environmental pollution have become increasingly common. Alleviating these problems involves addressing signal timing optimization and control, which are critical ...
Ruixiang Cheng +3 more
doaj +1 more source
Bilevel Optimization for Traffic Mitigation in Optimal Transport Networks
Physical Review Letters, 2023 Global infrastructure robustness and local transport efficiency are critical requirements for transportation networks. However, since passengers often travel greedily to maximize their own benefit and trigger traffic jams, overall transportation performance can be heavily disrupted.
Alessandro Lonardi, Caterina De Bacco
openaire +4 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Archives of TransportIssues related to braking and acceleration in vehicles represent both technical and environmental challenges, regardless of the type of drive, whether combustion or electric.
Marcin Koniak +3 more
doaj +1 more source
Optimization of Traffic Situation Using Roundabouts
Transportation Research Procedia, 2021 Abstract Transport is one of the essential elements of critical infrastructure. It is necessary to solve the traffic jam problem and threaten life, health, and property. However, there are several places where these problems are. There is required to solve this problem. One of them is in the selected village in the Zlin Region, Czech Republic.
Víchová, Kateřina +3 more
openaire +2 more sources