Results 141 to 150 of about 843,166 (295)
Traffic Safety Improvement via Optimizing Light Environment in Highway Tunnels. [PDF]
Int J Environ Res Public Health, 2022 Su B, Hu J, Zeng J, Wang R.
europepmc +1 more source
Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
Advanced Science, EarlyView.This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Investment in roads and traffic safety: linked to economic development? A European comparison. [PDF]
Environ Sci Pollut Res Int, 2023 Navarro-Moreno J +2 more
europepmc +1 more source
Advanced Science, EarlyView.Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo +20 more
wiley +1 more source
Effects of psychotropic drugs on ocular parameters relevant to traffic safety: A systematic review. [PDF]
Neurosci Biobehav Rev, 2022 Arkell TR +6 more
europepmc +1 more source
Light‐Harvesting Photothermal Hotspots Enabled by NIR Scattering‐Absorption Coupling
Advanced Science, EarlyView.By coupling the broadband scattering of nanodiamonds with the plasmonic absorption of gold nanostars, this work proposes a novel strategy for the active modulation of photon transport. This strategy creates localized photothermal hotspots in turbid media and achieves a supra‐additive heating efficiency, thereby providing a universal platform for low ...
Zebin Wu +17 more
wiley +1 more source
Original and Low-Cost ADS-B System to Fulfill Air Traffic Safety Obligations during High Power LIDAR Operation. [PDF]
Sensors (Basel), 2023 Peyrin F +3 more
europepmc +1 more source
Advanced Science, EarlyView.This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon +21 more
wiley +1 more source
Traffic safety knowledge gain of ambulance drivers after simulator-based training. [PDF]
BMC Med Educ, 2022 Prohn MJ, Herbig B.
europepmc +1 more source
Advanced Science, EarlyView.ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li +8 more
wiley +1 more source