Advanced Science, EarlyView.A novel metal‐supramolecular nanoplatform (FLM@VC) enables efficient brain delivery via meningeal lymphatic vessels (MLVs), bypassing the blood‐brain barrier (BBB) through subcutaneous administration. It reprograms tumor‐associated macrophages (TAMs) and remodels the MLVs to promote DC trafficking and CD8+ T cell activation.
Chenxi Zhang +11 more
wiley +1 more source
Enhancing traffic safety analysis with digital twin technology: integrating vehicle dynamics and environmental factors into microscopic traffic simulation. [PDF]
Sci RepXu G +6 more
europepmc +1 more source
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Linkage of Medicare insurance claims to police-reported motor vehicle crashes: advancing traffic safety research in older adult populations. [PDF]
Inj EpidemiolLu FW +5 more
europepmc +1 more source
Magneto‐X Effects in Magnetic Soft Materials and Their Applications
Advanced Science, EarlyView.This review systematically explores magnetic soft materials (MSMs), a novel class of composites that transform under magnetic fields. It catalogs fundamental “Magneto‐X” effects, classifies materials by their matrix and magnetic fillers, and highlights transformative applications in soft robotics, biomedical devices, flexible electronics, etc. Finally,
Ziyin Xiang +5 more
wiley +1 more source
SafeTraffic Copilot: adapting large language models for trustworthy traffic safety assessments and decision interventions. [PDF]
Nat CommunZhao Y, Wang P, Zhao Y, Du H, Yang HF.
europepmc +1 more source
Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
Advanced Science, EarlyView.This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
The influence of heatwaves on traffic safety in five cities across Québec with different thermal landscapes. [PDF]
Inj EpidemiolNazif-Munoz JI +5 more
europepmc +1 more source
The effect of human mobility and control measures on traffic safety during COVID-19 pandemic. [PDF]
PLoS One, 2021 Zhang J +5 more
europepmc +1 more source
Light‐Harvesting Photothermal Hotspots Enabled by NIR Scattering‐Absorption Coupling
Advanced Science, EarlyView.By coupling the broadband scattering of nanodiamonds with the plasmonic absorption of gold nanostars, this work proposes a novel strategy for the active modulation of photon transport. This strategy creates localized photothermal hotspots in turbid media and achieves a supra‐additive heating efficiency, thereby providing a universal platform for low ...
Zebin Wu +17 more
wiley +1 more source