Results 171 to 180 of about 166,211 (300)

Review of Risk Communication Strategies and Existing Occupant Protection Safety Messages: Supplemental Technical Report [PDF]

open access: yes
DTNH2216-P-00102This project included tasks designed to identify psychological and communication theory to support traffic safety campaigns, identify campaigns currently using theory, obtain information from States about current traffic safety campaigns,
Eby, David W   +7 more
core  

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

open access: yesAdvanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru   +6 more
wiley   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright   +8 more
wiley   +1 more source

Evaluation of Community-Oriented Enforcement Demonstration Projects [PDF]

open access: yes
DTNH2215C00024This project evaluated effectiveness of two law enforcement agencies\u2019 use of data-driven approaches to traffic enforcement in Missouri and Oklahoma, supported by community-oriented policing to improve traffic safety and boost community
Alonge, Mark A   +3 more
core  

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

open access: yesAdvanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim   +8 more
wiley   +1 more source

Risk Communication Strategies and Existing Alcohol- Impaired and Distracted Driving Safety Messages [Traffic Tech]

open access: yes
This edition of Traffic Tech briefly describes a longer report as well as its supplemental appendix. Communication campaigns are widely used to promote traffic safety, safe driving practices and knowledge of traffic laws, and otherwise educate the public.
United States. Department of Transportation. National Highway Traffic Safety Administration. Office of Behavioral Safety Research
core  

Targeting DNGR‐1 with Fangchinoline Elevates Dendritic Cell Antigen Cross‐Presentation‐Mediated Antitumor Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao   +19 more
wiley   +1 more source

The influence of heatwaves on traffic safety in five cities across Québec with different thermal landscapes. [PDF]

open access: yesInj Epidemiol
Nazif-Munoz JI   +5 more
europepmc   +1 more source

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