Results 31 to 40 of about 843,166 (295)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
COMPLIANCE TESTING OF IOWA’S SKID-MOUNTED SIGN DEVICE [PDF]
, 1999 A wide variety of traffic control devices are used in work zones, some of which are nont ormally found on the roadside or in the traveled way outsideofthe work zones.
Faller, Ronald K. +4 more
core +1 more source
A model of the vessel traffic process [PDF]
, 1990 A model of the total vessel traffic control process that includes the functioning of the human operator (HO) is presented. The vessel traffic services (VTSs) are modeled in their possible role of monitor, conflict detector, and advisor for the total ...
Hoogland, M. +2 more
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Severity of cyclist head injuries caused by impacts with vehicle structure and road surface
Journal of Biomechanical Science and Engineering, 2016 For cyclist fatalities in 2014 in Japan, the head was the most frequently injured body region. In the present study, the authors analyzed the features of cyclist head injuries in real-world traffic accidents using the data of patients who were taken to ...
Shoko OIKAWA +5 more
doaj +1 more source
Generating Comfortable, Safe and Comprehensible Trajectories for Automated Vehicles in Mixed Traffic
, 2018 While motion planning approaches for automated driving often focus on safety and mathematical optimality with respect to technical parameters, they barely consider convenience, perceived safety for the passenger and comprehensibility for other traffic ...
Lauer, Martin +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Development and research of a SS-level universal double-beam assembled bridge barrier
Scientific ReportsA wide variety of bridge barriers are used on highways. The bearing capacities of different types of deck slabs are measured in this study by applying the yield line theory to determine the worst-case scenario.
Qianmiao Bu +3 more
doaj +1 more source
Mathematics, 2023 In the Dempster–Shafer evidence theory framework, extremum analysis, which should be repeatedly executed for uncertainty quantification (UQ), produces a heavy computational burden, particularly for a high-dimensional uncertain system with multiple joint ...
Shengwen Yin +4 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source