Results 41 to 50 of about 166,211 (300)

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Study on Loosening Mechanisms of Fastening Bolt in High-Speed Train Brake Disc

Machines
Brake disc fastening bolts endure complex thermomechanical loads and are susceptible to loosening during emergency braking, making comprehensive analysis of their thermomechanical response and failure mechanism critical.
Shuguang Yao, Meng Tang, Jie Xing, Yating Long, Jingwen Tan, Xinyu Gu   +5 more
doaj   +1 more source

Cluster-Based 3-D Channel Modeling for Massive MIMO in Subway Station Environment

IEEE Access, 2018
In this paper, a massive multiple-input multiple-output (MIMO) channel measurement campaign with 256-element virtual rectangular array at the base station was conducted.
Jianzhi Li, Bo Ai, Ruisi He, Mi Yang, Qi Wang, Bei Zhang, Zhangdui Zhong   +6 more
doaj   +1 more source

Is safety in the eye of the beholder? Discrepancies between self-reported and proxied data on road safety behaviors—A systematic review

Frontiers in Psychology, 2022
Recent studies have problematized on the lack of agreement between self-reported and proxied data in the field of road safety-related behaviors. Overall, and although these studies are still scarce, most of them suggest that the way we perceive our own ...
Sergio A. Useche, Mireia Faus, Francisco Alonso   +2 more
doaj   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Effect of valve on ballistic performance in supercritical CO2 pneumatic launch

Journal of CO2 Utilization, 2023
To investigate the impact of the launch valve on the performance of the supercritical CO2 pneumatic launch, a numerical model was developed based on the principles of mass and energy conservation. Specifically, the thermos-physical properties of real gas
Jiaqiang Wang, Tian Li, Zixuan Zhang, Shujian Yao, Zhaijun Lu   +4 more
doaj   +1 more source

Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing

Advanced Materials, EarlyView.
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long, Huanyu Zhou, Jaewan Ko, Hongwei Tan, Jaemin Lim, Yanfei Zhao, Daehan Kang, Eojin Yoon, Gyeong‐Tak Go, Somin Kim, Seung‐Woo Lee, Chan‐Yul Park, Hyojun Choi, Hyeran Kim, Hyung Joong Yun, Sung Hyuk Park, Kwan Sik Park, Jeong Woo Park, Mungeun Kim, Yong Soo Cho, Ho Won Jang, Wenqiang Yang, Min Hyuk Park, Wan Ki Bae, Sebastiaan van Dijken, Joona Bang, Tae‐Woo Lee   +26 more
wiley   +1 more source

Persistent Traffic Offenders: Alcohol Consumption and Personality as Predictors of Driving Disqualification

European Journal of Psychology Applied to Legal Context, 2019
Traffic safety is an important social problem. Many accidents are due to non-compliance with traffic regulations. Serious or repeated offenses are sanctioned with penalty points or court conviction, and sanctions can lead to disqualification from driving.
Ana Martí-Belda, Juan C. Pastor, Luis Montoro, Patricia Bosó, Javier Roca   +4 more
doaj   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

Advanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen, Xiaoyu Wang, Jilin Fan, Bi Wang, Hanghang Fang, Yurui Wang, Hao Cui, Mohammad Roufarshbaf, Ekaterina Savina, Alexandra Valeske, Quim Peña, Yang Shi, Andreas Herrmann, Twan Lammers, Mathias Hornef, Roman Barmin, Thomas Lisson, Georg Schmitz, Anne Rix, Fabian Kiessling   +19 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source