Results 41 to 50 of about 236 (109)
The Straits of Malacca and Singapore are the second busiest routes in the world that are used as international navigation routes that have the potential to be contaminated by cross-border oil spills. Various international legal instruments such as MARPOL 73/78 Annex I to VI regulate the prevention, reduction and control of pollution at sea.
Oktima Wuryantari +2 more
openaire +1 more source
PD‐L1 in Ovarian Cancer: Immune Evasion, Tumor‐Intrinsic Signaling, and Chemoresistance
The “Dual Shield” model of PD‐L1 in ovarian cancer. On the outside, PD‐L1 engages PD‐1 to inactivate T cells and drive immune evasion (immune shield). Inside the tumor cell, PD‐L1 activates AKT–mTOR, enhances DNA repair, rewires metabolism, supports autophagy, and enforces stemness programs—collectively creating a chemoresistance shield.
Zhiyang Xu +3 more
wiley +1 more source
Integrative single‐cell multi‐omics analysis reveals molecular heterogeneity among piriform cortex principal neurons and identifies Reln+ superficial‐layer neurons as a selectively vulnerable population in Alzheimer's disease. Cross‐region comparison with entorhinal cortex layer II neurons reveals a shared Gpc5‐high/Sort1‐low vulnerability‐associated ...
Jiayue Meng +9 more
wiley +1 more source
IUCN‐defined extant distribution of the Indo‐Pacific finless porpoise (Neophocaena phocaenoides), overlaid with occurrence records, global Marine Protected Areas (MPAs), and Important Marine Mammal Areas (IMMAs). ABSTRACT Prior to this study, the narrow‐ridged finless porpoise (Neophocaena asiaeorientalis) had been extensively studied across East Asia,
Manokaran Kamalakannan +7 more
wiley +1 more source
High‐Content CRISPR Screening: Methods and Applications
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang +6 more
wiley +1 more source
Co‐Flowering Plant Species in a Glasshouse Boost Both Strawberry Production and Bee Health
Integrating co‐flowering plants into glasshouse strawberry systems creates a “win‐win” synergy where floral diversification enhances stingless bee vitality and crop visitation. This approach increased A‐grade fruit from 25% to 70%, demonstrating that strategic biodiversity integration optimises both pollinator health and sustainable agricultural ...
Sindhu Sheoran +4 more
wiley +1 more source
River Sand and Gravel Mining: Global Drivers, Impacts, and Pathways for Sustainable Management
Abstract River sand and gravel are mined worldwide at volumes that now rival their natural replenishment, yet quantitative knowledge of this mining activity and its consequences lags far behind many other global environmental pressures. We synthesize 411 peer‐reviewed studies published since 1974 within a new Driver‐to‐Management Pathway for ...
Edward Park +25 more
wiley +1 more source
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu +7 more
wiley +1 more source
Leveraging urban greenspaces to bolster regional conservation priorities
This article demonstrates that urban greenspaces currently excluded from the San Francisco Bay Area's regional conservation plan offer significant, measurable conservation value. We found these overlooked areas host vital biodiversity and critically improve habitat connectivity, highlighting that incorporating urban greenspaces will be key in meeting ...
Cesar O. Estien +5 more
wiley +1 more source
A Quasi-Intelligent Maritime Route Extraction from AIS Data. [PDF]
Onyango SO, Owiredu SA, Kim KI, Yoo SL.
europepmc +1 more source

