Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Analyzing Mega-mobility Systems in Smart Cities: A Macro-Micro Integration with Feedback Paradigm Empowered by Artificial Intelligence. [PDF]
Wang Z +10 more
europepmc +1 more source
Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
Towards Dynamic V2X Infrastructure: Joint Deployment and Optimization of 6DMA-Enabled RSUs. [PDF]
Wu X +5 more
europepmc +1 more source
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin +19 more
wiley +1 more source
Research on multi-channel access strategy based on congestion control with burst traffic in CRNs. [PDF]
Xu Q, Zhang Q, Bi Y, Gaber J.
europepmc +1 more source
Advancements in accident-aware traffic management: a comprehensive review of V2X-based route optimization. [PDF]
Zohir HM +3 more
europepmc +1 more source
Integration of Multi-Sensor Fusion and Decision-Making Architecture for Autonomous Vehicles in Multi-Object Traffic Conditions. [PDF]
Nguyen HN +6 more
europepmc +1 more source
5G High Density Demand Dataset in Liverpool City Region, UK. [PDF]
Maheshwari MK +5 more
europepmc +1 more source

