Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
APPLICATION OF FUZZY LOGIC TO TRAFFIC SIGNAL CONTROL UNDER MIXED TRAFFIC CONDITIONS [PDF]
Traffic signal control is commonly used at road intersections to minimise vehicular delay. Fixed time control shows good results in conditions where there is a little fluctuation in traffic demand, however in time-varying traffic
Yulianto, Budi
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Double Deep Q-Network with a Dual-Agent for Traffic Signal Control
Adaptive traffic signal control (ATSC) based on deep reinforcement learning (DRL) has shown promising prospects to reduce traffic congestion. Most existing methods keeping traffic signal phases fixed adopt two agent actions to match a four-phase ...
Jianfeng Gu +3 more
doaj +1 more source
CityFlow: A Multi-Agent Reinforcement Learning Environment for Large Scale City Traffic Scenario
Traffic signal control is an emerging application scenario for reinforcement learning. Besides being as an important problem that affects people's daily life in commuting, traffic signal control poses its unique challenges for reinforcement learning in ...
Ding, Yaoyao +9 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Backpressure based traffic signal control considering capacity of downstream links
Congestion is a kind of expression of instability of traffic network. Traffic signal control keeping traffic network stable can reduce the congestion of urban traffic.
Shenxue Hao +3 more
doaj +1 more source
Detection of malicious data in vehicular ad-hoc networks for traffic signal control applications
Effective applications of vehicular ad hoc networks in traffic signal control require new methods for detection of malicious data. Injection of malicious data can result in significantly decreased performance of such applications, increased vehicle ...
Bernas, Marcin, Placzek, Bartlomiej
core +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
A platoon based model for urban traffic networks: identification, modeling and distributed control [PDF]
Urban traffic control poses a challenging problem in terms of coordinating the different traffic lights that can be used in order to influence the traffic flow.
Boel, René, Marinica, Nicolae-Emanuel
core +1 more source

