Results 121 to 130 of about 6,545,702 (334)
Advanced Science, EarlyView.Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan +11 more
wiley +1 more source
A multi-agent model of traffic simulation around urban scenic spots: From the perspective of tourist behaviors. [PDF]
Heliyon, 2023 Cheng J, Wu L, Gao Y, Tian X.
europepmc +1 more source
International Journal of Informatics and Communication Technology (IJ-ICT), 2016 Computer traffic simulation is a widely used technique in modeling, coming up with and development of traffic networks and systems. It contains a various applications, like traffic forecasting, vehicle navigation devices and so on. This paper discusses about the various types of traffic simulators.
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SIMULATION STUDY OF TRAFFIC ACCIDENTS IN BIDIRECTIONAL TRAFFIC MODELS [PDF]
International Journal of Modern Physics C, 2010 Conditions for the occurrence of bidirectional collisions are developed based on the Simon–Gutowitz bidirectional traffic model. Three types of dangerous situations can occur in this model. We analyze those corresponding to head-on collision; rear-end collision and lane-changing collision.
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Advanced Science, EarlyView.PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia +14 more
wiley +1 more source
Simulation Modelling Practice and Theory, 2019 This paper introduces a general simulation framework that can allow the simulation of crashes and the evaluation of consequences on existing microsimulation packages. A specific family of simple and reproducible conflict indicators is proposed and applied to many case studies.
Astarita, Vittorio +1 more
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ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
Advanced Science, EarlyView.ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song +12 more
wiley +1 more source
Micro-simulation of Desired Speed for Temporary Work Zone with a New Calibration Method
Promet (Zagreb), 2016 Nowadays, the studies of parameter calibration for long-term work zones are limited to driver behaviour and car-following parameters, and no research was found related to calibration of the desired speed distributions during temporary work zones ...
Chi Zhang +3 more
doaj +1 more source
SYMBIOTIC TRAFFIC SIMULATION FRAMEWORK [PDF]
, 2015 Real time data from several traffic participants such as smart-phone users and vehicles equipped with GPS devices (taxi and bus fleets) is potentially available in the form of a continuous data stream in several mega cities. This real time data can be augmented with that from the traditional sensors for the implementation of several advanced traffic ...
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Advanced Science, EarlyView.Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan +11 more
wiley +1 more source