Results 171 to 180 of about 10,472,101 (345)

Simulation and control of the traffic of metro lines

, 1988
An original `state feedback' solution to the problem of traffic control on metro lines is presented. In addition, a dedicated traffic simulation software (SIMETRO) is described. This software allows to account for all kinds of security constraints and is
Simulation in the Factory of the Future and Simulation in Traffic Control. Proceedings of the European Simulation Multiconference, Bastin, Georges, Van Breusegem, V., Campion, Guy   +3 more
core  

A State‐Gated Metallo‐DNAzyme Framework Programs Tumor Stress Vulnerability Through Metabolic Licensing

Advanced Science, EarlyView.
A tumor‐state‐gated metallo‐DNAzyme framework integrates miR‐21/APE1‐responsive GLUT1 silencing with Ca/Cu‐partitioned metal–nucleic acid assembly and cystine loading. The framework first weakens glucose‐dependent metabolic buffering and then amplifies copper‐ and disulfide‐associated stress, converting tumor metabolic adaptation into programmable ...
Xiaodong Ma, Lingyun He, Xinru Wang, Yuanyuan Wei, Chengcheng Li, Jiaqi Yan, Weijian Sun, Xian Shen, Hongbo Zhang   +8 more
wiley   +1 more source

Machine learning-based incident duration prediction integrated with microscopic traffic simulation for expressway resilience evaluation. [PDF]

Sci Prog
Nakkliang R, Boongrapue N, Meesit R.
europepmc   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Collision risk analysis in the merging area of interchanges using Monte Carlo traffic simulation. [PDF]

PLoS One
Liu D, Li F, Yang Z, Xu G, Zheng X, Yue S, Gao Y.   +6 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Enhancing traffic safety analysis with digital twin technology: integrating vehicle dynamics and environmental factors into microscopic traffic simulation. [PDF]

Sci Rep
Xu G, Chen J, Wang Z, Zhou A, Schrader M, Bittle J, Shao Y.   +6 more
europepmc   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

Parallel Traffic Flow Simulation of Freeway Networks: Phase 2

, 1997
Explicit and implicit numerical methods for solving simple macroscopic traffic flow continuum models have been studied and efficiently implemented in traffic simulation codes in the past.
Chronopoulos, Anthony
core  

Expression of Concern: Platoon Interactions and Real-World Traffic Simulation and Validation Based on the LWR-IM. [PDF]

PLoS One
PLOS ONE Editors.
europepmc   +1 more source