Results 81 to 90 of about 745,871 (341)
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Интеллект. Инновации. Инвестиции, 2019 Relevance. A significant lag in the pace of development of the road network in the cities from the rate of motorization causes an increase in the problem of bandwidth exhaustion.
D.H. Nesterenko
doaj +1 more source
Spatio-Temporal Graph Convolutional Networks: A Deep Learning Framework for Traffic Forecasting
, 2018 Timely accurate traffic forecast is crucial for urban traffic control and guidance. Due to the high nonlinearity and complexity of traffic flow, traditional methods cannot satisfy the requirements of mid-and-long term prediction tasks and often neglect ...
Yin, Haoteng, Yu, Bing, Zhu, Zhanxing
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
, 1986 Progress Report No. 120 is the report of the May-August 1986 study of free flow automobile and truck speeds on tangent, level and dry sections of rural interstate, rural 4-lane, rural 2-lane and urban interstate highways in Indiana. The results of this report show that all types of vehicles, on all types of Indiana highways, had an average free flow ...
David Cochran, Leroy Gray
openaire +2 more sources
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Traffic Danger Recognition With Surveillance Cameras Without Training Data
, 2018 We propose a traffic danger recognition model that works with arbitrary traffic surveillance cameras to identify and predict car crashes. There are too many cameras to monitor manually.
Chen, Xiangqun +3 more
core +1 more source
Advanced Engineering Materials, EarlyView.This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal +2 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Influence of built-in strain sensor on the mechanical properties of asphalt mixture
工程科学学报The pursuit of intelligence and smartness in road infrastructure is critical for the advancement of road engineering. Embedded strain sensors serve as a vital tool for sensing strain within pavement structures.
Li LIU +5 more
doaj +1 more source