Results 51 to 60 of about 9,675,732 (304)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A simulation-based dynamic traffic assignment model with combined modes [PDF]

open access: yes, 2013
This paper presents a dynamic traffic assignment (DTA) model for urban multi-modal transportation network by con­structing a mesoscopic simulation model.
Meng, Meng   +7 more
core   +1 more source

Designing Post-Disaster Restoration Schemes for Traffic Networks based on Network Topological Indicators [PDF]

open access: yesE3S Web of Conferences
Identifying key road segments and prioritizing their protection to enhance the resilience of road networks against crisis events remains a pressing issue.
Yao Yitao   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Deployment of Tire Pressure Monitoring Systems for Traffic Monitoring and Safety Purposes [PDF]

open access: yes, 2011
In this paper, ideas and challenges of utilizing Tire Pressure Monitoring Systems’ (TPMS) communication messages for traffic purposes are described. Following the principle of the frequently and successfully tested Bluetooth technology approach to derive
Schulz, Jan, Junghans, Marek
core  

Traffic control signal design manual

open access: yes, 2009
Title from PDF cover (DOT web site, viewed Dec. 3, 2009).; Previously published: Manual of traffic control signal design. [Wethersfield, Conn] : Dept. of Transportation, Bureau of Highways, Office of Engineering, Division of Traffic, [1984].; Includes ...

core   +1 more source

Relieving the Impact of Transit Signal Priority on Passenger Cars through a Bilevel Model

open access: yesJournal of Advanced Transportation, 2017
Transit signal priority (TSP) is an effective control strategy to improve transit operations on the urban network. However, the TSP may sacrifice the right-of-way of vehicles from side streets which have only few transit vehicles; therefore, how to ...
Ding Wang, Wenxin Qiao, Chunfu Shao
doaj   +1 more source

Real-Time Vehicle Trajectory Prediction for Traffic Conflict Detection at Unsignalized Intersections

open access: yesJournal of Advanced Transportation, 2021
Real-time prediction of vehicle trajectory at unsignalized intersections is important for real-time traffic conflict detection and early warning to improve traffic safety at unsignalized intersections.
Qianxia Cao   +4 more
doaj   +1 more source

Traffic avoidance and separation system [PDF]

open access: yes2017 International Conference on Advances in Computing, Communications and Informatics (ICACCI), 2017
Aircraft need to be separated from other aircraft by either a minimum vertical distance of 1000ft or by a minimum horizontal distance of 5NM to avoid mid-air collisions. Traffic Alert and Collision Avoidance System (TCAS) work well as a tactical safety backups to avoid collision, but cannot perform separation assurance.
Balaji Raman Katta, Irfan Madani
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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