Results 71 to 80 of about 9,675,732 (304)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

A linear programming joint optimization model of overnight train timetabling and maintenance planning on high-speed railway

Scientific Reports
Maintenance activities on high-speed railway (HSR) facilities are essential for ensuring operational integrity, typically scheduled during the overnight window (0:00–6:00) to avoid disrupting daytime services.
Tianwei Zhang, Wei Liang, Hangyu Ji, Chuntian Zhang   +3 more
doaj   +1 more source

Urban Priority Pass: Fair signalised intersection management accounting for passenger needs through prioritisation

Transportation Research Interdisciplinary Perspectives
Over the past few decades, efforts of road traffic management and practice have predominantly focused on maximising system efficiency and mitigating congestion from a system perspective.
Kevin Riehl, Anastasios Kouvelas, Michail A. Makridis   +2 more
doaj   +1 more source

Synthesis for Vesicle Traffic Systems [PDF]

, 2018
18 pages, 2 figures, 1 ...
Ashutosh Gupta, Somya Mani, Ankit Shukla 0003   +2 more
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Traffic Management Systems [PDF]

This study uses regression analysis to evaluate long-run traffic management system performance. Three important traffic management systems in the Twin Cities metro area - Ramp Metering, Variable Message Signs (VMS), and Freeway Service Patrol (the ...
Wei Chen, David Levinson
core  

Distinguishing between Rural and Urban Road Segment Traffic Safety Based on Zero-Inflated Negative Binomial Regression Models

Discrete Dynamics in Nature and Society, 2012
In this study, the traffic crash rate, total crash frequency, and injury and fatal crash frequency were taken into consideration for distinguishing between rural and urban road segment safety.
Xuedong Yan, Bin Wang, Meiwu An, Cuiping Zhang   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Oregon traffic safety performance plan. Annual report

, 1998
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Fiscal year 1998-Vols.

core  

Nautical traffic simulation with multi-agent system [PDF]

, 2013
This paper describes a microscopic nautical traffic simulation model based on multi-agent system. The ship traffic is produced from the behavior of autonomous agents that represent ships.
Coen van Gulijk, Han Ligteringen, Fangliang Xiao, Van Gulijk, Coen, Ale, B.J.M. (author), Ale, B. (author), Ale, B.J.M., Ligteringen, H. (author), Van Gulijk, C. (author), Xiao, F. (author), Ligteringen, Han, Van Gulijk, C., Xiao, F., Ben Ale, Xiao, Fangliang, Ale, Ben, Ligteringen, H.   +16 more
core   +2 more sources