Results 101 to 110 of about 904,971 (330)

CXCR4, the master regulator of neutrophil trafficking in homeostasis and disease

open access: yesEuropean Journal of Clinical Investigation, 2018
Chemokines play a critical role in orchestrating the distribution and trafficking of neutrophils in homeostasis and disease.
K. De Filippo, S. Rankin
semanticscholar   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Mucins and their receptors in chronic lung disease

open access: yesClinical & Translational Immunology, 2020
There is growing recognition that mucus and mucin biology have a considerable impact on respiratory health, and subsequent global morbidity and mortality.
Emma Denneny   +5 more
doaj   +1 more source

Southwest Border Violence: Issues in Identifying and Measuring Spillover Violence [PDF]

open access: yes, 2010
[Excerpt] There has been a recent increase in the level of drug trafficking-related violence within and between the drug trafficking organizations in Mexico. This violence has generated concern among U.S.
Eddy, Mark   +6 more
core   +2 more sources

A Non-Parametric Learning Approach to Identify Online Human Trafficking

open access: yes, 2016
Human trafficking is among the most challenging law enforcement problems which demands persistent fight against from all over the globe. In this study, we leverage readily available data from the website "Backpage"-- used for classified advertisement ...
Alvari, Hamidreza   +2 more
core   +1 more source

Research trends on human trafficking: a bibliometric analysis using Scopus database

open access: yesGlobalization and Health, 2018
BackgroundHuman trafficking is a crime against humanity. It is also a serious threat to global health and security. Globalization has made human trafficking an easier task for the criminal organizations.
W. Sweileh
semanticscholar   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Establishment of a synchronized tyrosinase transport system revealed a role of Tyrp1 in efficient melanogenesis by promoting tyrosinase targeting to melanosomes

open access: yesScientific Reports
Tyrosinase (Tyr) is a key enzyme in the process of melanin synthesis that occurs exclusively within specialized organelles called melanosomes in melanocytes.
Hikari Nakamura, Mitsunori Fukuda
doaj   +1 more source

Sex Trafficking: Proposals in the 114th Congress to Amend Federal Criminal Law [PDF]

open access: yes, 2015
[Excerpt] The 114th Congress opened with the introduction of a number of proposals that address human trafficking, particularly sex trafficking. Among them were proposals to amend existing federal criminal law, which would expand the coverage of federal ...
Doyle, Charles
core   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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