Results 81 to 90 of about 495,024 (299)

HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA

open access: yesBiomolecules, 2015
Unspliced, genomic HIV-1 RNA (vRNA) is a component of several ribonucleoprotein complexes (RNP) during the viral replication cycle. In earlier work, we demonstrated that the host upframeshift protein 1 (UPF1), a key factor in nonsense-mediated mRNA decay
Lara Ajamian   +8 more
doaj   +1 more source

Trafficking [PDF]

open access: yesSpace and Culture, 2004
In cities the world over, we are able to determine stability in daily existence, to identify with our social spaces, because modes of transport have become essential components of subjective autonomy. But would it not be just as accurate to say that in transit, modern life puts the self in abeyance? The author argues that the ways we allow ourselves to
openaire   +4 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Establishment of a synchronized tyrosinase transport system revealed a role of Tyrp1 in efficient melanogenesis by promoting tyrosinase targeting to melanosomes

open access: yesScientific Reports
Tyrosinase (Tyr) is a key enzyme in the process of melanin synthesis that occurs exclusively within specialized organelles called melanosomes in melanocytes.
Hikari Nakamura, Mitsunori Fukuda
doaj   +1 more source

Mucins and their receptors in chronic lung disease

open access: yesClinical & Translational Immunology, 2020
There is growing recognition that mucus and mucin biology have a considerable impact on respiratory health, and subsequent global morbidity and mortality.
Emma Denneny   +5 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Help eliminate human trafficking.; Other title: Trafico humano

open access: yes, 2013
Spanish version of: Help eliminate human trafficking.; "Mike DeWine, Ohio Attorney General."; "Created: 4/4/2013 ..."--Document properties screen.; "Protecting Ohio's Families.

core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

South Carolina Human Trafficking Task Force newsletter special edition

open access: yes, 2020
This quarterly newsletter is released by the South Carolina Human Trafficking Task Force. As South Carolina's anti-human trafficking movement continues to grow, the State Task Force designed this newsletter to promote information sharing and ...
South Carolina Human Trafficking Task Force
core   +1 more source

South Carolina Human Trafficking Task Force newsletter special edition

open access: yes, 2021
This quarterly newsletter is released by the South Carolina Human Trafficking Task Force. As South Carolina's anti-human trafficking movement continues to grow, the State Task Force designed this newsletter to promote information sharing and ...
South Carolina Human Trafficking Task Force
core  

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