Results 61 to 70 of about 157,979 (250)
In cities the world over, we are able to determine stability in daily existence, to identify with our social spaces, because modes of transport have become essential components of subjective autonomy. But would it not be just as accurate to say that in transit, modern life puts the self in abeyance? The author argues that the ways we allow ourselves to
openaire +4 more sources
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
2015 Annual report. 2016: Jan. 5.
Annual; Began with Jan. 2008.; "Report Prepared by the Permanent Commission on the Status of Women (PCSW)."; Volume for 2014 originally published in print and online with the title: Annual report, was reformatted online with the title: Recommendations to
Connecticut. Trafficking in Persons Council.
core +1 more source
In Vivo Tissue-wide Synchronization of Mitochondrial Metabolic Oscillations
Little is known about the spatiotemporal coordination of mitochondrial metabolism in multicellular organisms in situ. Using intravital microscopy in live animals, we report that mitochondrial metabolism undergoes rapid and periodic oscillations under ...
Natalie Porat-Shliom +5 more
doaj +1 more source
Anthropology of sexual exploitation [PDF]
In this paper, the authors observe sexual exploitation from an anthropological perspective. They analyze the rational, ethical, emotional and mythological dimensions of human sexuality.
Lalić Velibor, Kešetović Želimir
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Identification of Rab30 as a novel regulator of tubular endosomes
Tubular-shaped recycling endosomes, known as tubular endosomes, are present in certain types of cells, including HeLa cells, and they regulate the recycling of clathrin-independent endocytosed (CIE) cargo proteins to the plasma membrane.
Shumpei Nakashima, Mitsunori Fukuda
doaj +1 more source
Revisiting Rab7 Functions in Mammalian Autophagy: Rab7 Knockout Studies
Rab7 (or Ypt7 in yeast) is one of the well-characterized members of the Rab family small GTPases, which serve as master regulators of membrane trafficking in eukaryotes.
Yoshihiko Kuchitsu, Mitsunori Fukuda
doaj +1 more source
Other title: Human trafficking
Palm card.; "Mike DeWine, Ohio Attorney General."; "Created: 7/20/2016 ..."--Document properties screen.; "Protecting Ohio's Families."On verso: Recognizing the problem: Sex trafficking ; Labor trafficking ; Report suspicious ...
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