Results 41 to 50 of about 599,042 (350)

The Parched Earth of Cooperation: How to Solve the Tragedy of the Commons in International Environmental Governance [PDF]

, 2016
This article proposes a way to strengthen international environmental agreements, such as the Paris Agreement and the Kyoto Protocol. Multilateral environmental agreements such as these are extremely fragile.
Druzin, Bryan H.
core   +1 more source

Demography and the tragedy of the commons

, 2010
Individual success in group-structured populations has two components. First, an individual gains by outcompeting its neighbors for local resources. Second, an individual's share of group success must be weighted by the total productivity of the group ...
Alexander, Alexander, Alizon, Avilés, Bulmer, Buss, Charlesworth, Crespi, Dionisio, Frank, Frank, Frank, Frank, Frank, Frank, Frank, Frank, Frank, Frank, Gardner, Grafen, Hamilton, Hamilton, Hamilton, Hamilton, Hardin, Johnstone, Kokko, Lehmann, Leigh, Levin, Lion, Maynard Smith, Maynard Smith, Nadell, Nagelkerke, Nunney, Oster, Rankin, Rankin, Reece, Szathmáry, Szathmáry, Taylor, Taylor, Thucydides, van Tienderen, West, Wilson   +48 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Inhuman Humanity: On the Theater of Angela Di Maso

Pamiętnik Teatralny, 2023
This article discusses Angela Di Maso’s theater, which is a reflection on contemporary society and aims to awaken audiences from social conformity and consumerism.
Andrea F. De Carlo, Angela Di Maso
doaj   +1 more source

Compounding Tragedy [PDF]

Policy, Politics, & Nursing Practice, 2007
The case of six health professionals imprisoned and facing execution in Libya only deepens the tragedy of an HIV outbreak among hospitalized children in the late 1990s. Worldwide attention has been focused on this case. Among the issues at stake is the ability of health professionals to provide critically needed services without fear of being turned ...
openaire   +2 more sources

Tragedy of the commons in the chemostat [PDF]

bioRxiv, 2017
We present a proof of principle for the phenomenon of the tragedy of the commons that is at the center of many theories on the evolution of cooperation. We establish the tragedy in the context of a general chemostat model with two species, the cooperator
M. Schuster, E. Foxall, D. Finch, Hal L. Smith, P. De Leenheer   +4 more
semanticscholar   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Tragedy, Solidarity, and Impartiality. The Meaning of Hannah Arendt’s Thinking for Our Narrational Identity [PDF]

Phainomena, 2019
The aim of the article is to outline the meaning of the tragic component of action in Hannah Arendt’s theory of politics, and to relate it to the problem of modern storytelling and historiography by means of the concepts of solidarity and impartiality ...
Paulina Sosnowska
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source