Results 41 to 50 of about 447,838 (312)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Design and engineering of human TRAIL variants [PDF]

open access: yes, 2006
TRAIL is een humaan eiwit dat bepaalde typen kankercellen aanzet tot geprogrammeerde celdood (apoptose) terwijl het normale cellen met rust laat. Hierdoor is TRAIL een veel­belovend potentieel anti kanker geneesmiddel.
Sloot, Albert Martinus   +1 more
core   +14 more sources

TRAIL Microcard Update

open access: yes, 2022
Presentation discussing the status of the TRAIL Microcard Scanning Project at the University of North Texas. This presentation was given at the Technical Report Archive and Image Library (TRAIL) annual meeting on May 25 ...
Phillips, Mark Edward
core  

Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth [PDF]

open access: yes, 2009
Background: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to ...
Amy Prosser   +51 more
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Exploring Sentiment Analysis and Visitor Satisfaction along Urban Liner Trails: A Case of the Seoul Trail, South Korea

open access: yesLand
Increasing public health awareness has stressed the significance of the mental and physical benefits of outdoor activities. Government involvement and support for urban redevelopment projects in Korea, such as Seoul Dulle-gil, connected previously ...
Sumin Lee, Won Ji Chung, Chul Jeong
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Glucosamine Enhances TRAIL-Induced Apoptosis in the Prostate Cancer Cell Line DU145

open access: yesMedicines, 2019
Background: Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells in cancer patients. However, patients often develop TRAIL resistance; thus, agents that can sensitize cells to TRAIL therapy would be ...
Chao Sun   +3 more
doaj   +1 more source

On the campaign trail [PDF]

open access: yesBMJ, 1983
One of the aspects of a general election campaign that the voters never see is the way that a party leader's speech grows and grows in performance. The point is that the actual audience at each rally hears basically the same speech, but with sections added to highlight the issue of the day.
openaire   +2 more sources

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