Results 271 to 280 of about 395,211 (318)
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On the TRAIL to apoptosis

Cytokine & Growth Factor Reviews, 2002
Apoptosis in mammalian cells can be initiated through two major interrelated pathways, one involving engagement of the TNF family of death receptors, the other involving the release of cytochrome c from mitochondria. Unlike other members of the TNF ligand family, TNF-related apoptosis-inducing ligand (TRAIL) preferentially induces apoptosis in tumor ...
Baetu, Tudor, Hiscott, John
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Technology on the Trail

Proceedings of the 2018 ACM Conference on Supporting Groupwork, 2018
The Technology on the Trail workshop will examine the encroachment of technology into hiking and outdoor adventures, with a focus on identifying and developing ways for technology to support positive and mutually beneficial connections among people. These connections include both intentional ones helpful in collecting scientific data, supporting the ...
D. Scott McCrickard   +6 more
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TRAIL/TRAIL‐R in hematologic malignancies

Journal of Cellular Biochemistry, 2010
AbstractDefects in apoptosis are observed in many cancer cell types and contribute in a relevant way to tumorigenesis. Apoptosis is a complex and well‐regulated cell death program that plays a key role in the control of cell homeostasis, particularly at the level of the hematopoietic system.
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Snail trail

ACM SIGGRAPH 2012 Art Gallery, 2012
A snail invents the wheel and goes through a cultural evolution to finally get back to its origin. The basic idea of the work is inspired by processes of exponential acceleration, which can be observed at different levels. Thus, the evolution of life process.
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On the Oregon trail

British Medical Bulletin, 1995
On the eve of the 21st century, governments around the world are struggling to resolve the dual problems of health care cost and access. My own experience in addressing these issues as they manifest themselves in the US, and particularly in the state of Oregon, convinces me that successful health care reform, anywhere in the world, must sooner or later
J, Kitzhaber, A M, Kemmy
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Targeting TRAIL

Bioorganic & Medicinal Chemistry Letters, 2019
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), also known as Apo2L, has been investigated in the past decade for its promising anticancer activity due to its ability to selectively induce apoptosis in tumoral cells by binding to TRAIL receptors (TRAIL-R).
George Nicolae Daniel Ion   +2 more
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The TRAIL of Death

Apoptosis, 1998
The TNF ligand family member termed TRAIL has been shown to induce apoptosis in a wide variety of transformed cell lines. The normal functions of this cytokine in vivo remain, however, relatively unknown. The complexity of this biological system has now increased unexpectedly with the identification of four distinct receptors for TRAIL, two of which ...
R G, Goodwin, C A, Smith
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Blazing the trail

The Lancet Oncology, 2001
When Charles Darwin set sail on the Beagle in 1831, he took with him some rather alarming matches. Known as Prometheans, after the fire-stealing Titan of Greek mythology, they were not to be trifled with. In fact, the modern match-user could be forgiven for not recognising them as matches at all.
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The Ivory Trail

Scientific American, 2009
This article discusses the poaching of animals in Africa. The economics of the trade in ivory, demand for which declined in Western nations after a ban in its trade under the United Nations Convention on International Trade in Endangered Species, is considered. The use of DNA forensics to determine the sources of ivory, which is poached for the benefit
Samuel K, Wasser   +2 more
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Blazing a trail

Nursing Standard, 1990
Coronary heart disease remains the biggest killer in the United Kingdom, despite the trend towards healthier living and much greater public awareness of risk factors. Nearly a quarter of a million people will the this year from the epidemic of heart disease.
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