Results 51 to 60 of about 312,207 (267)
eLife, 2016 The ability of a wild baboon to acquire and exploit social information depends on its individual characteristics and its position within various social networks.
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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Clinical EpigeneticsBackground Human aging and white blood cell (WBC) count are complex traits influenced by multiple genetic factors. Predictors of chronological age have been developed using epigenetic clocks.
Manli Sun +8 more
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Targeting of keloid with TRAIL and TRAIL-R2/DR5
Journal of Dermatological Treatment, 2020 Keloid is a common and frequently-occurring disease in plastic surgery, and its ugly appearance and itching symptoms bring mental and life pain to patients. However, the clinical treatment of keloid, such as drug injection treatment, surgical resection, cryotherapy, laser treatment and other therapeutic effects are poor.
Pengfei, Sun +3 more
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
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REM: International Engineering JournalSoil provides important support for anthropogenic activities, and earthen trails, which have always been present in the natural landscape, are routes of access to various tourist attractions. In recent decades, trails have been widely used as a method of
Ricardo Eustáquio Fonseca Filho +3 more
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PASOS Revista de Turismo y Patrimonio Cultural, 2017 El running se ha convertido en poco tiempo en un deporte de masas, generando todo un negocio a su alrededor y un impacto económico importante en aquellas localidades que albergan este tipo de eventos.
FEDERICO SOLER VAYÁ +1 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
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Journal of Threatened Taxa, 2019 Dugong Dugong dugon (Müller, 1776) is the only herbivorous marine mammal distributed along the tropical and subtropical oceans of the Indo-Pacific regions.
Deepak Apte +2 more
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