Results 111 to 120 of about 449,889 (313)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Appalachian Trail in North Carolina
, 2014 In 1930, the Carolina Appalachian Trail Club was organized for the purpose of completing the western North Carolina segment of the Appalachian Trail. Its home was in Asheville.
Carolina Appalachian Trail Club;
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Ecological classification and cattle breeding in Africa
Genetics Selection Evolution, 1982 Trail JCM
doaj +1 more source
, 1963 Photograph of a busload of Buckeye Trail hikers, 1963. The Buckeye Trail winds for about 1,444 miles through Ohio from Lake Erie near Cleveland to the Ohio River near Cincinnati. The Buckeye Trail Association, a non-profit organization created in June of
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Trail Blazer - Volume 68, Number 28 [PDF]
, 1995 Morehead State Trail Blazer published on May 1, 1996. This issue of the Trail Blazer has a misprinted volume number.https://scholarworks.moreheadstate.edu/trail_blazer/2532/thumbnail ...
Morehead State University. Trail Blazer.
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Journal of Agriculture and Environment for International DevelopmentThe survey aimed to examine the factors influencing local tourists’ Willingness-To-Pay (WTP) for the ecopark, focusing on tree crown architecture and the georeferencing of indigenous trees.
Eric D. Bimmoy +2 more
doaj +1 more source
Buckeye Trail Association members at the Grandma Gatewood Memorial Hiking Trail
, 1984 Emily Gregor and Ann Quadrano, members of the Buckeye Trail Association, shown standing at the memorial marking the entrance to the Grandma Gatewood Memorial Hiking Trail in Hocking County, Ohio.
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Trail Blazer - Unnumbered Volume and Issue [PDF]
, 1966 Morehead State Trail Blazer published on March 24, 1966. This issue of the Trail Blazer has no written volume or issue number.https://scholarworks.moreheadstate.edu/trail_blazer/1703/thumbnail ...
Morehead State University. Trail Blazer.
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