Results 161 to 170 of about 459,788 (312)
Trail City Council, 1969 - T. Steven, Trail councillor
, 1969 Following amalgamation of Trail and ...
core
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Trail City Council, 1969 - V.D. Arcuri, Trail councillor
, 1969 Following amalgamation of Trail and ...
core
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Acquired TRAIL Resistance Promotes Cancer Stemness and Malignant Behavior through CD44-SPHK1-STAT3 Signaling in Colorectal Cancer. [PDF]
Biomol Ther (Seoul)Kim SL, Jin BC, Seo SY, Kim SW.
europepmc +1 more source
Trail City Council, 1969 - M.M. Morrison, Trail councillor
, 1969 Following amalgamation of Trail and ...
core
FEBS Open Bio, EarlyView.A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li +7 more
wiley +1 more source
Integrated conservation of linear heritage landscapes from a biocultural diversity perspective: A case study of the Huizhou-Hangzhou Ancient Trail, China. [PDF]
PLoS OneDong Y, Pan C, Pan S, Zhang L.
europepmc +1 more source