Results 81 to 90 of about 138,899 (263)
, 1980 Photograph of Janice Trail at his home near Claytor Lake in Pulaski County ...
Trail, Janice;
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Acta Botânica Brasílica, 2011 O estudo analisou a vegetação herbácea ao longo de uma trilha de uso público intensivo nos parques Natural Municipal Nascentes de Paranapiacaba (PNMNP) e Estadual da Serra do Mar (PESM).
Luísa Almeida Maciel +2 more
doaj +1 more source
Buckeye Trail Becomes Ohio's Official Hiking Trail
, 1967 Governor James Rhodes signing a bill to make the Buckeye Trail the official hiking trail of Ohio, April 27, 1967. Pictured with Governor Rhodes (from left to right) are Kenneth D.
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Bulletin de la Dialyse à Domicile, 2019 En France, près de 3 millions de personnes sont touchées par les maladies du rein. L’insuffisance rénale chronique touche environ 80 000 personnes. Sur ces 80 000 per¬sonnes touchées, 44 % d’entre elles bénéficient d’une greffe de rein, et 56 % sont ...
Fabrice Huré
doaj +1 more source
Recreational Demand for Equestrian Trail-Riding [PDF]
Using data collected from a combination of on-site and on-line surveys, this study examines recreational demand for equestrian trail-riding in Kentucky.
Blackwell, Melanie +3 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 1963 Photograph of a busload of Buckeye Trail hikers, 1963. The Buckeye Trail winds for about 1,444 miles through Ohio from Lake Erie near Cleveland to the Ohio River near Cincinnati. The Buckeye Trail Association, a non-profit organization created in June of
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source