Results 61 to 70 of about 138,899 (263)
Arctic ScienceAs part of an Inuit-led initiative, a collaborative research project combined scientific methods and Inuit knowledge to design an environmentally friendly and climate change-resilient access route from the community of Kugluktuk to Kugluk Territorial ...
Michel Allard +7 more
doaj +1 more source
, 1981 "March 1981."; Cover title of accompanying text: Comprehensive plan.; Spine title of accompanying text: Appalachian Trail comprehensive plan.; "Source Data: Map base is Geological Survey 1:2,500,000 scale map, dated 1972."; Accompanied by text ...
core
Targeting of keloid with TRAIL and TRAIL-R2/DR5
Journal of Dermatological Treatment, 2020 Keloid is a common and frequently-occurring disease in plastic surgery, and its ugly appearance and itching symptoms bring mental and life pain to patients. However, the clinical treatment of keloid, such as drug injection treatment, surgical resection, cryotherapy, laser treatment and other therapeutic effects are poor.
Pengfei, Sun +3 more
openaire +2 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
PASOS Revista de Turismo y Patrimonio Cultural, 2017 El running se ha convertido en poco tiempo en un deporte de masas, generando todo un negocio a su alrededor y un impacto económico importante en aquellas localidades que albergan este tipo de eventos.
FEDERICO SOLER VAYÁ +1 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Clinical EpigeneticsBackground Human aging and white blood cell (WBC) count are complex traits influenced by multiple genetic factors. Predictors of chronological age have been developed using epigenetic clocks.
Manli Sun +8 more
doaj +1 more source
REM: International Engineering JournalSoil provides important support for anthropogenic activities, and earthen trails, which have always been present in the natural landscape, are routes of access to various tourist attractions. In recent decades, trails have been widely used as a method of
Ricardo Eustáquio Fonseca Filho +3 more
doaj +1 more source
, 1996 Part history, part resource book, part guide, and part photographic essay, The Mormon Trail Yesterday and Today is an essential reference for readers of all ages who are interested in the Mormon trek west.
Hill, William E. +2 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source