Results 221 to 230 of about 138,899 (263)
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On the Oregon trail

British Medical Bulletin, 1995
On the eve of the 21st century, governments around the world are struggling to resolve the dual problems of health care cost and access. My own experience in addressing these issues as they manifest themselves in the US, and particularly in the state of Oregon, convinces me that successful health care reform, anywhere in the world, must sooner or later
J, Kitzhaber, A M, Kemmy
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Targeting TRAIL

Bioorganic & Medicinal Chemistry Letters, 2019
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), also known as Apo2L, has been investigated in the past decade for its promising anticancer activity due to its ability to selectively induce apoptosis in tumoral cells by binding to TRAIL receptors (TRAIL-R).
George Nicolae Daniel Ion   +2 more
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The TRAIL of Death

Apoptosis, 1998
The TNF ligand family member termed TRAIL has been shown to induce apoptosis in a wide variety of transformed cell lines. The normal functions of this cytokine in vivo remain, however, relatively unknown. The complexity of this biological system has now increased unexpectedly with the identification of four distinct receptors for TRAIL, two of which ...
R G, Goodwin, C A, Smith
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TRAIL in the Airways

2004
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is an important immunomodulatory factor that may play a role in the structural changes observed in the asthmatic airways. In vitro as well as in vivo studies have evidenced a dual role for TRAIL: it can either function as a pro- or anti-inflammatory cytokine on inflammatory cells ...
Noreen M, Robertson   +5 more
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TRAIL and TRAIL receptors in patients with laryngeal cancer

Head & Neck, 2015
AbstractBackgroundTumor necrosis factor–related associated‐inducing ligand (TRAIL) is a death ligand currently under clinical trials for laryngeal carcinoma.MethodsParaffin‐embedded tissues from 40 patients with laryngeal carcinoma and 20 patients with benign laryngeal pathologies were retrospectively analyzed using immunohistochemistry in terms of ...
Evren, Erkul   +6 more
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Trail Characteristics as Correlates of Urban Trail Use

American Journal of Health Promotion, 2007
Purpose. The purpose of this study was to identify the environmental correlates of urban trail use. Design. Three multiuse urban trails at least 15 miles in length were selected. Trails were divided into one-half-mile segments (N = 102
Reynolds, Kim D   +6 more
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Blazing the trail

The Lancet Oncology, 2001
When Charles Darwin set sail on the Beagle in 1831, he took with him some rather alarming matches. Known as Prometheans, after the fire-stealing Titan of Greek mythology, they were not to be trifled with. In fact, the modern match-user could be forgiven for not recognising them as matches at all.
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Trail Magic

JAMA
In this narrative medicine essay, an obstetrician-gynecologist describes a day in her life of crossing state lines to provide abortion care for people from all over the Southeast US in the post-Dobbs era.
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The Wolf's Trail

Creative Nursing
Stardust and Story: Indigenous Wisdom and the Wolf's Trail . Through the lens of Indigenous Knowledge, this piece integrates Indigenous teachings with contemporary ideas about consciousness and quantum potentiality, offering a paradigm for addressing systemic imbalance ...
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Functional expression of TRAIL receptors TRAIL-R1 and TRAIL-R2 in esophageal adenocarcinoma

European Journal of Cancer, 2006
The tumour necrosis factor (TNF) related apoptosis-inducing ligand (TRAIL/Apo2L) is a member of the TNF superfamily that preferentially induces apoptosis in cancer cells, while sparing normal cells. TRAIL induces apoptosis by interacting with its receptors TRAIL-R1 and TRAIL-R2.
Mamoun, Younes   +4 more
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